filamins

Subscribe to Selected New Research on filamins

112 relevant articles (0 outcomes, 6 trials/studies) found for this Bio-Agent

Description: found in smooth muscle & non-muscle cells; RefSeq NM_001456 (FLNA protein), NM_001458 (FLNC protein), NM_001457 (FLNB)

Also Known As:

280 kDa actin-binding protein; ABP-278 protein, human; FLN1protein, human; FLN2 protein, human; FLNA protein, human; FLNB protein, human; FLNC protein, human; alpha-filamin; beta-filamin; cheerio protein, Drosophila; cher protein, Drosophila; filamin; filamin 1; filamin 1-like protein; filamin 2; filamin A; filamin A, alpha (actin binding protein 280), human; filamin B; filamin B, beta (actin binding protein 278), human; filamin C; filamin C, gamma (actin binding protein 280), human; merofilamins

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins

Proteins: 56712

Cytoskeletal Proteins: 482

Microfilament Proteins: 51

filamins: 112

Contractile Proteins: 288

filamins: 112

Macromolecular Substances: 43

Polymers: 3635

Biopolymers: 143

Microfilament Proteins: 51

filamins: 112

Experts

1.	van der Ven, Peter F M: 3 articles (12/2007 - 11/2004)
2.	Vorgerd, Matthias: 2 articles (12/2007 - 08/2005)
3.	Bruchertseifer, Vera: 2 articles (12/2007 - 08/2005)
4.	Lochmüller, Hanns: 2 articles (12/2007 - 08/2005)
5.	Schröder, Rolf: 2 articles (12/2007 - 08/2005)
6.	Fürst, Dieter O: 2 articles (12/2007 - 08/2005)
7.	Kley, Rudolf A: 2 articles (12/2007 - 08/2005)
8.	Huebner, Angela: 2 articles (12/2007 - 08/2005)
9.	Robertson, Stephen P: 2 articles (05/2007 - 12/2006)
10.	Andermann, F: 2 articles (01/2005 - 08/2001)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 10/01/2008 - "Using human melanoma cells, which do not express filamin A, we showed that receptor down-regulation, functional desensitization and trafficking are deficient in the absence of FLA (Onoprishvili et al. Mol Pharmacol 64:1092-1100, 2003)" 11/03/2007 - "Immunofluorescence microscopy revealed that p73alpha remained in the cytoplasm in A7 melanoma cells stably expressing filamin A, whereas it was localized in the nucleus of filamin A-deficient M2 cells" 09/01/2007 - "BK(Ca) channels do not traffic to the plasma membrane in M2 melanoma cells, which lack filamin A, but normal trafficking is seen in A7 cells, which express filamin A, or in M2 cells transiently transfected with filamin A" 03/15/2006 - "Here we report the rheological properties of cultured hsFLNa (filamin-A)-expressing (FIL+) and hsFLNa-deficient (FIL-) melanoma cells" 03/15/2006 - "Filamin-a and rheological properties of cultured melanoma cells." Order ALL the reference details at left...
2.	Syndrome 08/15/2007 - "Filamin A studies in other children with FG syndrome would help to confirm this association." 08/01/2004 - "While prior reports have shown that mutations in the filamin A (FLNA) gene can cause X-linked dominant PH, an increasing number of studies suggest the existence of additional PH syndromes" 08/15/2007 - "Indeed, a previously unreported FLNA missense mutation (P1291L) was detected in our patient with FG syndrome, thus supporting this hypothesis and indicating that FG syndrome could now be added to the list of Filamin A-related disorders" 08/15/2007 - "Filamin A mutation is one cause of FG syndrome." 05/15/2007 - "Missense mutations of the FLNA gene, which encodes for the protein filamin A, have recently been shown to cause OPD2 and the allelic syndromes otopalatodigital type 1, Melnick-Needles, and frontometaphyseal dysplasia" Order ALL the reference details at left...
3.	Adhesions 11/14/2008 - "We identified the actin cross-linking molecule filamin B as a novel binding partner for intracellular adhesion molecule-1 (ICAM-1)" 07/02/2004 - "Integrin-filamin binding plays an important role in adhesion-mediated control of the actin cytoskeleton" 06/27/2003 - "Filamin A is an established structural component of cell-matrix adhesion sites" 01/10/2000 - "Previous studies of filamin family members have determined that these proteins are involved in actin reorganization and signal transduction cascades associated with cell migration, adhesion, differentiation, force transduction, and survival" 11/14/2008 - "Reducing filamin B expression in primary human endothelial cells resulted in reduced recruitment of ICAM-1 to endothelial docking structures, reduced firm adhesion of the leukocytes to the endothelium, and inhibition of transendothelial migration" Order ALL the reference details at left...
4.	Muscular Diseases (Myopathy) 12/01/2007 - "Clinical and morphological phenotype of the filamin myopathy: a study of 31 German patients." 08/01/2005 - "A mutation in the dimerization domain of filamin c causes a novel type of autosomal dominant myofibrillar myopathy." 12/01/2007 - "Mutations in the filamin C gene (FLNC) cause a myofibrillar myopathy (MFM), morphologically characterized by focal myofibrillar destruction and abnormal accumulation of several proteins within skeletal muscle fibres" 01/15/2003 - "An examination of biopsies from patients with multi-minicore myopathy, central core myopathy and neurogenic target fibers with core-like target formations (TF) revealed strong reactivity of all the cores and target formations with two different anti-filamin C antibodies" 10/01/2008 - "RECENT FINDINGS: The most important recent advance in the myofibrillar myopathies has been the discovery that mutations in Z band alternatively spliced PDZ-containing protein and filamin C, as well as in desmin, alphaB-crystallin and myotilin, result in similar pathologic alterations in skeletal muscle that are typical of myofibrillar myopathy" Order ALL the reference details at left...
5.	Periventricular Nodular Heterotopia 08/01/2008 - "Bilateral periventricular nodular heterotopia is most commonly an X-linked disorder that involves mutations in the filamin A (FLNA) gene, but an autosomal recessive form and sporadic forms have been identified" 06/01/2008 - "Periventricular nodular heterotopia is characterized by aggregates of grey matter adjacent to the lateral ventricle and is mainly linked to mutations in the Filamin A (FLNA) gene" 06/01/2006 - "BACKGROUND: Mutations of the filamin A locus (FLNA) on Xq28 have been established in girls with periventricular nodular heterotopia and in patients with otopalatodigital and overlapping phenotypes, the pathogenesis of these phenotypes being thought to be quite distinct" 12/01/2002 - "Bilateral periventricular nodular heterotopia due to filamin 1 gene mutation: widespread glomeruloid microvascular anomaly and dysplastic cytoarchitecture in the cerebral cortex." 03/26/2002 - "OBJECTIVE: To examine the clinical and MRI associations in bilateral periventricular nodular heterotopia (BPNH) (MIM # 300049) in two families segregating a missense mutation and a C-terminal deletion of the filamin 1(FLN1) gene" Order ALL the reference details at left...

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	mu Opioid Receptors (mu Opioid Receptor)
3.	DNA (Deoxyribonucleic Acid)
4.	Carrier Proteins (Binding Protein)
5.	filamins
6.	Actinin
7.	Talin
8.	Vinculin
9.	Myosins (Myosin)
10.	Desmin

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