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dihydroneopterin triphosphate

Also Known As:

dihydro-neopterin triphosphate; dihydroneopterin triphosphate, (2R,3S)-isomer

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Pteridines: 147
      - Pterins: 160
        Biopterins: 249
        Neopterin: 1756
        dihydroneopterin triphosphate: 2
Enzymes and Coenzymes: 1
- Coenzymes: 558
  - Biopterins: 249
    - Neopterin: 1756
      - dihydroneopterin triphosphate: 2

Experts

1.	Hanson, Andrew D: 1 article (07/2009)
2.	Hyde, John E: 1 article (07/2009)
3.	Jeanguenin, Linda: 1 article (07/2009)
4.	Lara-Núñez, Aurora: 1 article (07/2009)
5.	Pribat, Anne: 1 article (07/2009)
6.	Ziemak, Michael J: 1 article (07/2009)
7.	de Crécy-Lagard, Valérie: 1 article (07/2009)

Related Diseases

1.	Malaria 07/01/2009 - "A similar PTPS paralog from the malaria parasite Plasmodium falciparum is known to form HMDHP from dihydroneopterin triphosphate in vitro and has been proposed to provide a bypass to the FolB step in vivo. "
2.	Alzheimer Disease (Alzheimer's Disease) 07/01/1984 - "Brains from subjects with senile dementia of Alzheimer type retain their ability to synthesis neopterin and have normal dihydropteridine reductase activity, indicating a specific loss of ability to convert dihydroneopterin triphosphate to tetrahydrobiopterin."

Related Drugs and Biologics

1.	Neopterin
2.	Dihydropteridine Reductase (6,7 Dihydropteridine Reductase)
3.	6-pyruvoyltetrahydropterin synthase (PTPS)
4.	sapropterin (tetrahydrobiopterin)