bromfenacoum (Ratak)

Also Known As:

Ratak; brodifacoum; 3-(3-(4'-bromobiphenyl-4-yl)-1,2,3,4-tetrahydronaphth-1-yl)-4-hydroxycoumarin; Talon-G; WBA 8119; superwarfarin; 2H-1-Benzopyran-2-one, 3-(3-(4'-bromo(1,1'-biphenyl)-4-yl)-1,2,3,4-tetrahydro-1-naphthalenyl)-4-hydroxy-

Networked: 139 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        4-Hydroxycoumarins: 2
        bromfenacoum: 139
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        4-Hydroxycoumarins: 2
        bromfenacoum: 139

Experts

1.	Feinstein, Douglas L: 11 articles (01/2021 - 01/2015)
2.	Rubinstein, Israel: 10 articles (01/2021 - 01/2015)
3.	Weinberg, Guy: 8 articles (05/2019 - 01/2015)
4.	van Breemen, Richard: 5 articles (05/2019 - 01/2016)
5.	Nosal, Daniel G: 4 articles (01/2021 - 03/2019)
6.	van Breemen, Richard B: 3 articles (01/2021 - 01/2020)
7.	Kalinin, Sergey: 3 articles (05/2019 - 01/2016)
8.	Shen, Min: 3 articles (10/2016 - 10/2012)
9.	Xiang, Ping: 3 articles (10/2016 - 10/2012)
10.	Yan, Hui: 3 articles (10/2016 - 10/2012)

Related Diseases

1.	Poisoning 09/28/1998 - "None of the patients in our study died of superwarfarin poisoning. " 10/07/2022 - "Notes from the Field: Coagulopathy Associated with Brodifacoum Poisoning - Florida, December 2021." 05/18/2022 - "Here, we discuss a case of suspected superwarfarin poisoning to highlight the challenges in early diagnosis and the challenges we encountered in treatment management and ensuring compliance for long periods." 05/18/2022 - "Superwarfarin poisoning: challenges still remain." 05/01/2022 - "Powerful owls do not scavenge but prey upon arboreal marsupials, and generally not rodents, suggesting that brodifacoum is entering the powerful owl food web via accidental or deliberate poisoning of non-target species (possums). "
2.	Hemorrhage 10/01/2023 - "Brodifacoum exposure has been known to cause increased bleeding, as seen in this case. " 12/01/2019 - "Superwarfarin Exposure: An Important Uncommon Cause of Painless Bleeding." 10/01/2016 - "The toxicity of brodifacoum was dose-dependent, and the high-dose group obviously manifested toxicity with subcutaneous hemorrhage. " 07/01/2015 - "50-fold prolongation of PT occurred at higher brodifacoum dosages and correlated to hemorrhage found at necropsy. " 01/01/2011 - "Patients rarely consult physicians before developing coagulopathy or bleeding in most reported cases of superwarfarin intoxication. "
3.	Malabsorption Syndromes (Malabsorption Syndrome) 03/05/1996 - "In view of the absence of liver disease or malabsorption syndromes, long-acting anticoagulant ('superwarfarin') ingestion was suspected. " 09/01/2007 - "The combination of persistent coagulopathy, normal mixing studies, normal liver function tests and absence of hepatic failure or malabsorption syndromes lead to the suspicion of vitK dependent clotting factors deficiency due to superwarfarin poisoning. "
4.	Liver Failure 09/01/2007 - "The combination of persistent coagulopathy, normal mixing studies, normal liver function tests and absence of hepatic failure or malabsorption syndromes lead to the suspicion of vitK dependent clotting factors deficiency due to superwarfarin poisoning. "
5.	Munchausen Syndrome (Munchhausen Syndrome) 09/28/1998 - "All 7 children included in the study had accidentally ingested superwarfarin, 2 adults had Munchausen syndrome, and 1 teenager and 1 adult had attempted suicide using superwarfarin. " 09/28/1998 - "The patients who had accidentally ingested superwarfarin or attempted suicide using it were easily diagnosed, while diagnosis was markedly delayed for the 2 patients with Munchausen syndrome. "

Related Drugs and Biologics

1.	Vitamin K
2.	Warfarin (Coumadin)
3.	Factor VIIa (Activated Factor VII)
4.	recombinant FVIIa (rFVIIa)
5.	bromfenacoum (Ratak)
6.	Rodenticides
7.	bromadiolone
8.	difenacoum
9.	Blood Coagulation Factors (Coagulation Factor)
10.	flocoumafen

Related Therapies and Procedures

1.	Therapeutics
2.	Transplantation
3.	Plasma Exchange
4.	Injections
5.	Duration of Therapy