|1.||Leenen, Frans H H: 4 articles (05/2015 - 02/2002)|
|2.||Osborn, John W: 3 articles (02/2014 - 05/2008)|
|3.||Pavlov, Tengis S: 2 articles (01/2015 - 06/2013)|
|4.||Ilatovskaya, Daria V: 2 articles (01/2015 - 06/2013)|
|5.||Palygin, Oleg: 2 articles (01/2015 - 06/2013)|
|6.||Levchenko, Vladislav: 2 articles (01/2015 - 06/2013)|
|7.||Staruschenko, Alexander: 2 articles (01/2015 - 06/2013)|
|8.||Granados-Soto, Vinicio: 2 articles (12/2014 - 01/2009)|
|9.||Murbartián, Janet: 2 articles (12/2014 - 01/2009)|
|10.||Rocha-González, Héctor I: 2 articles (12/2014 - 01/2009)|
01/01/1990 - "The inclusion of benzamil, an amiloride analogue, 2 min before and during the Ca2(+)-free perfusion period prevented contracture development, restored force development, and almost totally eliminated the release of CPK and LDH from the muscle. "
01/01/1994 - "2. This dose of benzamil increased the contracture response of both types of muscle to halothane. "
01/01/1994 - "The effects of benzamil on in vitro contracture responses of human skeletal muscle to halothane."
01/01/1994 - "3. At a concentration of 1 microM, benzamil significantly reduced the contracture response to halothane of muscle from malignant hyperthermia individuals. "
01/01/1994 - "1. Inhibition of sodium-calcium exchange using 100 microM benzamil caused contracture development of in vitro skeletal muscle samples from humans susceptible to malignant hyperthermia, but not of samples from normal individuals. "
09/01/1991 - "Direct pharmacological blockade of the Na+,Ca2+ exchanger during anoxia with bepridil or benzamil also significantly improved recovery. "
09/01/2007 - "(3)After incubation with Benzamil, and then subjected the cells to anoxia, the following data were obtained: [Ca(2+)] i concentration (129.21+/-14.33) nmol/L, TNF-alpha content (6.78+/-0.52) ng/L and MDA (8.47+/-0.79) microg/L and they were all lower than only anoxia was applied (all P<0.01). "
|3.||Hypertension (High Blood Pressure)
05/01/2015 - "These mice exhibit enhanced pressor responses to CSF [Na(+)] as well as dietary salt-induced hypertension which both can be blocked by central infusion of the ENaC blocker benzamil. "
06/01/2013 - "Here, the ENaC inhibitor benzamil attenuated the development of hypertension in Dahl salt-sensitive rats. "
07/01/2002 - "Central infusions of benzamil prevent/reverse salt-induced hypertension in genetic models of salt-sensitive hypertension. "
02/01/2002 - "These findings suggest that benzamil-blockable brain FaNaChs represent the major mechanism through which a small increase in CSF Na(+) by ICV Na(+)-rich aCSF in Wistar rats or high salt intake in SHR initiates sympathoexcitation and hypertension. "
03/01/1998 - "Benzamil blockade of brain Na+ channels averts Na(+)-induced hypertension in rats."
01/28/2009 - "The purpose of this study was to assess the possible antinociceptive effect of the acid sensing ion channels (ASICs) inhibitors amiloride and benzamil after local peripheral administration in three models of inflammatory pain in rats. "
08/01/2013 - "Amiloride and benzamil showed antinocicepitve effects in several pain models through the inhibition of acid sensing ion channels (ASICs). "
|5.||Acute Lung Injury
02/18/2005 - "The observation suggests that in acutely injured lung treated with HFOV an ENaC blocker, benzamil, can be applied as a therapeutic drug for acute lung injury combing with HFOV."
02/18/2005 - "Benzamil, a blocker of epithelial Na(+) channel-induced upregulation of artery oxygen pressure level in acute lung injury rabbit ventilated with high frequency oscillation."
02/18/2005 - "To study if ENaC plays a key role in recovering P(aO(2)) from a decreased level to a normal one in acute lung injury, we applied benzamil (20microM, a specific blocker of ENaC) to the lung luminal space in acute lung injury treated with high frequency oscillation ventilation (HFOV) that is a lung-protective ventilation with a lower tidal volume and a smaller pressure swing than conventional mechanical ventilation (CMV). "
|3.||Sodium Channels (Sodium Channel)
|8.||Epithelial Sodium Channel
|9.||Estrogen Receptor Modulators (Antiestrogen)
|10.||Fura-2 (Fura 2)
|1.||Artificial Respiration (Mechanical Ventilation)