picumast

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12 relevant articles (3 outcomes, 4 trials/studies) found for this Bio-Agent

Description: RN & NM refer to di-HCl

Also Known As:

3,4-dimethyl-7-(4-(p-chlorobenzyl)piperazin-1-yl)propoxycoumarin.di-HCl; BM 15,100; BM 15100; BM-15100; 2H-1-benzopyran-2-one, 7-(3-(4-((4-chlorophenyl)methyl)-1-piperazinyl)propoxy)-3,4-dimethyl-, dihydrochloride

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

2-Ring Heterocyclic Compounds

Benzopyrans: 5

Coumarins: 132

picumast: 12

Related Diseases

1.	Asthma (Bronchial Asthma) 10/01/1989 - "Acceptability, safety and efficacy of picumast dihydrochloride on long-term use in patients with perennial bronchial asthma." 10/01/1989 - "Although this was an open study, analysis of diary card measurements and clinical assessments indicate that picumast dihydrochloride could represent a new and effective prophylactic therapy in the long-term management of bronchial asthma" 10/01/1989 - "The differences between the picumast dihydrochloride and placebo groups significantly favoured picumast dihydrochloride for improvements in mean number of daytime asthma attacks, morning tightness, aerosol use and sum of symptom scores" 10/01/1989 - "From reasons of these experimental data picumast dihydrochloride may be of a considerable value as a prophylactic agent in allergic bronchial asthma when given orally." 10/01/1989 - "Patients given picumast dihydrochloride demonstrated significant improvements compared with baseline in morning and evening peak flow and asthmatic symptoms like morning tightness, cough, dyspnoea, obstruction, number of asthma attacks during night and day, sum of asthmatic symptom scores, in vital capacity and Tiffeneau index, and a significant reduction of inhaled adjuvant medications" Get all the results and reference details, order at left...
2.	Seasonal Allergic Rhinitis (Hay Fever) 10/01/1989 - "Double-blind multicenter controlled clinical study comparing the efficacy of picumast dihydrochloride versus astemizole and placebo in patients with seasonal allergic rhinitis." 10/01/1989 - "It is concluded that picumast dihydrochloride offers a comparable alternative to terfenadine in the treatment of seasonal allergic rhinitis." 10/01/1989 - "A placebo-controlled comparison of the efficacy and tolerability of picumast dihydrochloride and terfenadine in patients with seasonal allergic rhinitis." 10/01/1989 - "Of 99 evaluable patients with seasonal allergic rhinitis, 33, 35, and 31 were treated with picumast dihydrochloride (3,4-dimethyl-7-[4-(4-chlorbenzyl)piperazine-1-yl]propoxycoumar in dihydrochloride) 1 mg, terfenadine 60 mg, and placebo, respectively, twice daily for 3 weeks" Get all the results and reference details, order at left...
3.	Cough 10/01/1989 - "Patients given picumast dihydrochloride demonstrated significant improvements compared with baseline in morning and evening peak flow and asthmatic symptoms like morning tightness, cough, dyspnoea, obstruction, number of asthma attacks during night and day, sum of asthmatic symptom scores, in vital capacity and Tiffeneau index, and a significant reduction of inhaled adjuvant medications" Get all the results and reference details, order at left...
4.	Nasal Obstruction 10/01/1989 - "The results of this study show that picumast dihydrochloride inhibits nasal obstruction and secretion in patients allergic to grass pollens following allergen challenge" 10/01/1989 - "Picumast dihydrochloride's ability to inhibit nasal obstruction after challenge was significantly better than that of placebo in statistical terms" Get all the results and reference details, order at left...
5.	Hypersensitivity (Allergy) 10/01/1989 - "Inhibition of the C3-zymosan-induced chemilumiescence of human leucocytes was taken as an indicator of the diminished liberation of mediators and inhibition of the histamine-induced contraction of isolated guinea-pig lung strips as an example for the antagonism of picumast dihydrochloride to mediators of allergic reactions" 07/01/1976 - "Profiles of different anti-allergy effects of a new histamine antagonist, BM 15,100 [proceedings]." Get all the results and reference details, order at left...
11 Diseases and 12 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Astemizole
2.	piperazine
3.	Ketotifen (Ketotifene)
4.	Histamine (Histamine Dihydrochloride)
5.	Pyrilamine (Mepyramine)
6.	Terfenadine (Seldane)
7.	Antigens
7 Drugs and Important Bio-Agents and 10 more articles analyzed in the Research Interface, order at left...

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