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tris(2-butoxyethyl) phosphate

inhibitor of drug-protein binding; present in stoppers of blood sample 'vacutainers'

Also Known As:

tributoxyethyl phosphate; 2-butoxyethanol phosphate (3:1)

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - tris(2-butoxyethyl) phosphate: 5

Experts

1.	Bastiaensen, Michiel: 2 articles (10/2020 - 10/2018)
2.	Covaci, Adrian: 2 articles (10/2020 - 10/2018)
3.	Chapman, Colin A: 1 article (10/2020)
4.	Mutegeki, Richard: 1 article (10/2020)
5.	Quirós, Rodolfo: 1 article (10/2020)
6.	Rothman, Jessica M: 1 article (10/2020)
7.	Steiniche, Tessa: 1 article (10/2020)
8.	Venier, Marta: 1 article (10/2020)
9.	Wang, Shaorui: 1 article (10/2020)
10.	Wasserman, Michael D: 1 article (10/2020)

Related Diseases

1.	Endometrial Neoplasms (Endometrial Cancer) 05/01/2016 - "The effects of six organophosphate flame retardants (OPFRs) tris(2-butoxyethyl) phosphate, tris(2-chloroethyl) phosphate, tris(1-chloro-2-propyl) phosphate, tris(methylphenyl) phosphate, tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), and triethyl phosphate on the activities of androgen receptor (AR), estrogen receptor (ER), and aryl hydrocarbon receptor (AhR) were assessed in human prostate and endometrial cancer cells. "
2.	Leiomyoma (Uterine Fibroids) 10/01/2020 - "The odds ratios (ORs) of uterine fibroids were significantly higher among the women with higher exposures to tris(1,3-dichloro-2-propyl) phosphate (TDCIPP) and tris(2-butoxyethyl) phosphate (TBOEP), di(2-ethylhexyl) terephthalate (DEHTP), DPrHpP, and di-(iso-nonyl)-cyclohexane-1,2-dicarboxylate (DINCH). "
3.	Hemorrhagic Fever with Renal Syndrome (HFRS) 10/06/2020 - "The most abundant chemicals were α-hexachlorocyclohexane (α-HCH), β-hexachlorocyclohexane (β-HCH), and hexachlorobenzene among OCPs across all sites, chlorpyrifos among CUPs in Costa Rica and Indiana, decabromodiphenylethane (DBDPE) in Costa Rica and Indiana and 2, 2', 4, 4'-tetrabromodiphenyl ether (BDE-47) in Uganda as HFRs, and tris(2-butoxyethyl) phosphate (TBOEP) as OPFRs across all sites. "
4.	Eczema 10/01/2018 - "A high OR of 2.86 (1.04-7.85) (>LOD vs <LOD) was found for hydroxy tris(2-butoxyethyl) phosphate (TBOEP)-OH and eczema. "
5.	Breast Neoplasms (Breast Cancer) 09/15/2023 - "Some OPFRs, i.e., tris(2-butoxyethyl) phosphate (TBOEP), tris(1,3-dichloroisopropyl) phosphate (TDCPP), tri-o-cresyl phosphate (TOCP) and triphenyl phosphate (TPHP), were found to inhibit activities of some transporters, such as organic anion transporter 3 (OAT3), organic anion transporting polypeptide (OATP) 1B1, OATP1B3, organic cation transporter 2 (OCT2) or breast cancer resistance protein (BCRP). "

Related Drugs and Biologics

1.	tris(1,3-dichloroisopropyl) phosphate
2.	Phosphates (Orthophosphate)
3.	Organic Anion Transporters
4.	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)
5.	Estrogen Receptors
6.	Androgen Receptors (Androgen Receptor)
7.	Proteins (Proteins, Gene)
8.	Organophosphates
9.	Peptides (Polypeptides)
10.	Hexachlorobenzene (HCB)