soluble immune response suppressor

released by concanavalin A activated spleen cells; protein or glycoprotein; MW between 48,000-67,000; also lipoprotein complex; do not confuse with systemic inflammatory response syndrome

Also Known As:

Networked: 11 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Brod, Staley A: 1 article (08/2011)
2.	Hood, Zachary M: 1 article (08/2011)

Related Diseases

1.	Nephrotic Syndrome (Syndrome, Nephrotic) 03/01/1989 - "The soluble immune response suppressor pathway in nephrotic syndrome." 05/01/1991 - "Serum analysis for soluble immune response suppressor was negative pre-nephrectomy, positive during each bout of nephrotic syndrome, and negative during each remission. " 01/01/1987 - "Soluble immune response suppressor (SIRS), a lymphokine that suppresses antibody production and delayed type hypersensitivity in vivo, has been detected in urine and serum from certain patients with nephrotic syndrome. " 07/01/1990 - "Previously, it has been determined that subjects with steroid-responsive nephrotic syndrome (SRNS) produce the lymphokine, soluble immune response suppressor (SIRS). " 07/01/1990 - "A regulatory system for soluble immune response suppressor production in steroid-responsive nephrotic syndrome."
2.	Schistosomiasis mansoni 10/01/1985 - "Production of the lymphokine soluble immune response suppressor (SIRS) during chronic experimental schistosomiasis mansoni."
3.	Proteinuria 04/01/1977 - "Young NZB/W mice, treated with injections of soluble immune response suppressor (SIRS)(supernatant from mouse spleen cells exposed to concanavalin A), showed decreased immunoglobulin levels, less antibody to cell nuclei, less proteinuria, and less renal pathology as compared with NZB/W mice receiving a control preparation. "
4.	Neoplasms (Cancer) 08/01/1986 - "Soluble immune response suppressor (SIRS) is a protein produced by activated suppressor T lymphocytes which inhibits division by tumor cells and plaque-forming cell (PFC) responses in vitro. "
5.	Leukocytosis (Pleocytosis) 01/01/1990 - "Inhibition of interleukin 1 (IL-1)-elicited leukocytosis and LPS-induced fever by soluble immune response suppressor (SIRS)."

Related Drugs and Biologics

1.	Steroids
2.	Proteins (Proteins, Gene)
3.	soluble immune response suppressor
4.	Theophylline (Theon)
5.	Peptides (Polypeptides)
6.	Melanocyte-Stimulating Hormones (MSH)
7.	Interleukin-1 (Interleukin 1)
8.	Interferon Type I
9.	Immunoglobulins (Immunoglobulin)
10.	Concanavalin A

Related Therapies and Procedures

1.	Nephrectomy
2.	Injections