|1.||Kuppusamy, Periannan: 3 articles (08/2011 - 06/2006)|
|2.||Hideg, Kálmán: 2 articles (08/2011 - 10/2007)|
|3.||Kálai, Tamás: 2 articles (08/2011 - 10/2007)|
|4.||Mandal, Rajarsi: 2 articles (10/2007 - 06/2006)|
|5.||Khan, Mahmood: 2 articles (10/2007 - 06/2006)|
|6.||Kutala, Vijay Kumar: 2 articles (10/2007 - 06/2006)|
|7.||Zhu, Hui-Kai: 1 article (11/2015)|
|8.||Zhao, Mei-Xin: 1 article (11/2015)|
|9.||Shi, Min: 1 article (11/2015)|
|10.||Dai, Tong-Lei: 1 article (11/2015)|
12/08/1989 - "Two nitrone spin traps 5,5-dimethyl pyrroline 1-oxide (Me2PnO) and 3,3,5,5-tetramethyl pyrroline 1-oxide (MePnO) have been separately perfused at a concentration of 40 mM during a sequence of 50 min of low-flow ischemia (1 ml/min) followed by 30 min of global ischemia and subsequent reperfusion at the control flow rate (14 ml/min). "
11/01/2000 - "A pyrroline derivative of mexiletine offers marked protection against ischemia/reperfusion-induced myocardial contractile dysfunction."
06/01/2006 - "Trimetazidine, TMZ-NH (TMZ modified with a pyrroline moiety), or TMZ-PhiNH (TMZ-NH with a phenyl substitute) were infused (50 microM) for 1 min before the onset of ischemia. "
10/01/2007 - "N-hydroxy-pyrroline modification of verapamil exhibits antioxidant protection of the heart against ischemia/reperfusion-induced cardiac dysfunction without compromising its calcium antagonistic activity."
|2.||Colonic Neoplasms (Colon Cancer)
06/01/1997 - "To test the protective effects of antioxidants (N-acetyl-L-cysteine (LNAC) and free-radical spin traps (5,5-dimethyl-1-pyrroline N-oxide and 2,2,6,6,-tetramethyl-1-piperidinyloxy) against NO-induced apoptosis, a human colon cancer cell line (COLO 205) was treated with NO, and its survival rate was evaluated both with and without antioxidant therapy. "
|4.||Dehydration (Water Stress)
11/20/2015 - "The adduct can be easily transformed into biologically attractive chiral β-trifluoromethylated pyrroline carboxylate in high yield via an isocyano group hydrolysis/cyclization/dehydration cascade reaction by treating with acid. "
04/14/2012 - "The first asymmetric synthesis of β-trifluoromethylated pyrroline carboxylates has been achieved by organocatalytic conjugated addition of adamantyl glycine imine to β-trifluoromethylated enones, followed by a deprotection/cyclization/dehydration sequence."
09/01/1976 - "This apparent stimulation of proline biosynthesis in wilted leaves was not observed when radioactive ornithine or P5C (Delta(1)-pyrroline-5-carboxylate, an intermediate following glutamate in proline synthesis) were used as proline precursors unless proline levels were high as a result of previous water stress. "
08/11/2011 - "The results showed that all DAP compounds induced a significant loss of cell viability in the human cancer cell lines tested; however, only pyrroline appended nitroxides (5c (Selvendiran, K.; Tong, L.; Bratasz, A.; Kuppusamy, L. "
05/01/1980 - "The best discriminators include two hepatic enzymes whose concentrations were decreased to less than 30% of normal (soluble glutamate dehydrogenase and the cold stable pyrroline-5-carboxylate reductase) and three for which it was elevated two to four-fold (hexokinase, peptidyl proline hydroxylase and thymidine kinase) in response to distant neoplasms. "
|4.||amyloid beta-protein (25-35)
|5.||alpha- (4- pyridyl- 1- oxide)- N- tert- butylnitrone
|7.||Amine Oxidase (Copper-Containing)
|8.||Glutamic Acid (Glutamate)