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2'-hydroxychalcone

Also Known As:

1-(2-hydroxyphenyl)-3-phenyl-2-propen-1-one

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bronikowska, Joanna: 1 article (01/2022)
2.	Czuba, Zenon P: 1 article (01/2022)
3.	Janeczko, Tomasz: 1 article (01/2022)
4.	Kostrzewa-Susłow, Edyta: 1 article (01/2022)
5.	Kłósek, Małgorzata: 1 article (01/2022)
6.	Buckle, Michael J C: 1 article (12/2021)
7.	Bukhari, Syed Nasir Abbas: 1 article (12/2021)
8.	Chee, Chin Fei: 1 article (12/2021)
9.	Lee, Vannajan Sanghiran: 1 article (12/2021)
10.	Nasir, Shah Bakhtiar: 1 article (12/2021)

Related Diseases

1.	Inflammation (Inflammations) 04/01/2006 - "In this study, we investigated the anti-inflammatory action of 2'-hydroxychalcone (2-HC) in a model of lipopolysaccharide (LPS)-induced inflammation in RAW 264.7 macrophages and examined the role of HO-1 in this process. " 11/01/2021 - "As HCMV infection affects inflammation pathways, especially prostaglandin E2 (PGE2) production via cyclooxygenase 2 enzyme (COX-2), we designed 2'-hydroxychalcone compounds to inhibit human cytomegalovirus. "
2.	Neoplasms (Cancer) 01/01/2022 - "Our results showed that all tested methoxy-derivatives of 2'-hydroxychalcone compounds significantly reduced ICAM-1 released by SW480 cancer cells. " 10/01/2016 - "A series of innovative copper(II) complexes of the general composition [Cu(Ln)(phen)]NO3 (1-8; phen=1,10-phenanthroline), involving 2'-hydroxychalcone {(E)-1-(2'-hydroxyphenyl)-3-phenylprop-2-en-1-one} derivatives (HLn) was synthesized, thoroughly characterized and screened for in vitro cytotoxicity against a panel of ten human cancer cell lines. "
3.	Diabetes Complications 11/01/2000 - "Inhibitory effects of synthetic 2'-hydroxychalcone derivatives on rat lens aldose reductase (RLAR) and on platelet aggregation were investigated for the prevention or the treatment of chronic diabetic complications. "
4.	Lung Neoplasms (Lung Cancer) 05/21/2014 - "A series of 2'-hydroxychalcone derivatives was synthesized and the effects of all the compounds on growth of A549 lung cancer cell were investigated. "
5.	Infections 11/01/2021 - "As HCMV infection affects inflammation pathways, especially prostaglandin E2 (PGE2) production via cyclooxygenase 2 enzyme (COX-2), we designed 2'-hydroxychalcone compounds to inhibit human cytomegalovirus. "

Related Drugs and Biologics

1.	Lipopolysaccharides
2.	Cyclooxygenase 2 (Cyclooxygenase-2)
3.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
4.	Dinoprostone (PGE2)
5.	Phenanthrolines
6.	Enzymes
7.	Copper
8.	Aldehyde Reductase (Aldose Reductase)