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fluorophosphate (sodium monofluorophosphate)

inhibits Phosphorylas phosphatase irreversibly; RN given refers to parent cpd
Also Known As:
sodium monofluorophosphate; Mono-Tridin; Na-MFP; Opfermann brand of sodium monofluorophosphate; ammonium monofluorophosphate; calcium monofluorophosphate; fluorophosphate hydrate, calcium salt; fluorophosphate, barium salt; fluorophosphate, calcium salt; fluorophosphate, diammonium salt; fluorophosphate, disodium salt; fluorophosphate, monoammonium salt; fluorophosphate, potassium salt; fluorophosphate, sodium salt; fluorophosphate, tin salt; fluorophosphate, vanadium salt; monofluorophosphate
Networked: 156 relevant articles (25 outcomes, 40 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. DeVizio, W: 7 articles (01/2012 - 06/2000)
2. Mateo, Luis R: 5 articles (09/2015 - 01/2009)
3. Zhang, Y P: 5 articles (08/2013 - 01/2009)
4. Cummins, D: 5 articles (08/2013 - 01/2009)
5. Mateo, L R: 5 articles (08/2013 - 01/2009)
6. DeVizio, William: 5 articles (01/2011 - 01/2004)
7. Zhang, Yun Po: 5 articles (01/2011 - 01/2004)
8. Auta, James: 4 articles (12/2011 - 03/2004)
9. Guidotti, Alessandro: 4 articles (12/2011 - 03/2004)
10. Jeffery, Peter: 3 articles (08/2015 - 01/2010)

Related Diseases

1. Dentin Sensitivity
02/18/2011 - "The dentine hypersensitivity was evaluated by a subject self-perceived short, sharp pain in visual analogue scale (VAS) in response to a blast of cold air from a triple syringe administered to a tooth surface in 1 cm. Test toothpastes, containing 5.53% potassium citrate and 0.76% sodium monofluorophosphate, and control toothpastes, containing only 0.76% sodium monofluorophosphate were delivered to the study subjects in the test and control group respectively. "
08/01/2015 - "To compare the efficacy of an anhydrous dentifrice containing 0.454% w/w stannous fluoride and a negative control dentifrice containing 1,000 ppm fluoride, as sodium monofluorophosphate, at reducing dentin hypersensitivity over 8 weeks with twice-daily brushing. "
03/01/2013 - "To compare the efficacy of a 0.454% w/w stannous fluoride containing anhydrous dentifrice and a negative control dentifrice containing 1,000 ppm fluoride (as sodium monofluorophosphate) at reducing dentin hypersensitivity over an 8-week period, following twice daily brushing. "
01/01/2005 - "The purpose of this study was to investigate the effect of a new toothpaste containing an antiplaque and antiinflammatory agent (0.3% triclosan), a desensitizing agent (5% potassium nitrate) and an anticaries agent (0.76% sodium monofluorophosphate (SMFP)) on gingival health, plaque formation and dentine hypersensitivity in a 12-week home study. "
05/01/2010 - "To present the results of an 8-week dentin hypersensitivity clinical study in which the efficacy of a new Pro-Argin formula toothpaste, with gentle whitening benefits, containing 8.0% arginine, a high cleaning calcium carbonate system, and 1450 ppm fluoride as sodium monofluorophosphate (MFP) was compared to that of a commercial Pro-Argin formula toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride as MFP and a negative control toothpaste containing calcium carbonate and 1450 ppm fluoride as MFP. "
2. Hypersensitivity (Allergy)
3. Gingivitis
08/01/1993 - "A double blind, seven month clinical study was conducted to determine the effects of three Triclosan containing test dentifrices on supragingival plaque, gingivitis and supragingival calculus formation compared to a 0.8 per cent monofluorophosphate-silica control dentifrice. "
01/01/1998 - "The objective of this 6-month, double-blind, clinical study, conducted in harmony with American Dental Association (ADA) guidelines, was to evaluate the efficacy of a dentifrice containing 2% zinc citrate and 0.76% sodium monofluorophosphate in a silica base (zinc citrate dentifrice) for the control of supragingival plaque and gingivitis, compared to a control dentifrice containing 0.76% sodium monofluorophosphate in a silica base (control dentifrice). "
01/01/1998 - "Thus, in accordance with the 1986 guidelines published by the ADA and the 1994 revision published by the Task Force on Design and Analysis in Dental and Oral Research, the results of this study support the conclusion that a dentifrice containing 2% zinc citrate and 0.76% sodium monofluorophosphate in a silica base is clinically efficacious for the control of supragingival plaque and gingivitis."
09/01/2015 - "To evaluate the efficacy of a test regimen (TR) integrating the use of a commercially available triclosan, PVM/MA copolymer, and sodium fluoride containing toothpaste, an alcohol-free, fluoride-free cetylpyridinium chloride (CPC) mouthwash, and a manual toothbrush with cheek and tongue cleaner compared to a negative control regimen (NCR) integrating a commercially available 0.76% sodium monofluorophosphate toothpaste, a manual toothbrush and a fluoride-free and alcohol-free non-antibacterial mouthwash in the reduction and control of established plaque and gingivitis after 4 weeks of product use. "
08/01/1993 - "A double blind, 7-month parallel clinical study was conducted to determine the effect of a dentifrice containing 0.3 per cent Triclosan and 0.75 per cent zinc citrate in a 0.8 per cent sodium monofluorophosphate/silica base on supragingival plaque, gingivitis and supragingival calculus formation, compared to a 0.8 per cent monofluorophosphate/silica control dentifrice. "
4. Postmenopausal Osteoporosis
5. Dental Calculus

Related Drugs and Biologics

1. Dentifrices (Dentifrice)
2. Fluorides
3. Arginine (L-Arginine)
4. Sodium Fluoride (Ossin)
5. Calcium Carbonate (Limestone)
6. Toothpastes
7. Silicon Dioxide (Sand)
8. Calcium
9. Potassium Chloride
10. Tin Fluorides (Floran)

Related Therapies and Procedures

1. Hormone Replacement Therapy (Therapy, Hormone Replacement)
2. Toothbrushing
3. Induced Hypothermia
4. Electrodes (Electrode)
5. Cardiopulmonary Bypass (Heart-Lung Bypass)