|1.||Sibley, Colin P: 2 articles (01/2016 - 07/2012)|
|2.||Dilworth, Mark R: 2 articles (01/2016 - 07/2012)|
|3.||Aplin, John D: 1 article (01/2016)|
|4.||Crocker, Ian P: 1 article (01/2016)|
|5.||Charnock, Jayne C: 1 article (01/2016)|
|6.||Westwood, Melissa: 1 article (01/2016)|
|7.||Erlenwein, Sarah-Vanessa: 1 article (01/2014)|
|8.||von Kaisenberg, Constantin S: 1 article (01/2014)|
|9.||von Versen-Höynck, Frauke: 1 article (01/2014)|
|10.||Darashchonak, Natallia: 1 article (01/2014)|
12/09/1991 - "These routes are: (1) a non-saturable, Na(+)-independent route formally indistinguishable from diffusion; (2) a saturable, Na(+)-independent route inhibitable by the analog BCH and identifiable with system L; (3) a low-affinity, Na(+)-dependent component (Km = 3 mM) which can be attributed to the activity of system A since it is adaptively enhanced by amino acid starvation and suppressed by the characterizing analog MeAIB and (4) a high-affinity, Na(+)-dependent route (Km = 0.05 mM). "
12/10/1983 - "Amino acid starvation of pancreatic islets during 11 h of tissue culture resulted in a 2-fold increase in MeAIB transport."
07/10/1983 - "Amino acid starvation enhances MeAIB-dependent Na+ influx. "
07/10/1983 - "Furthermore, efflux of [14C]MeAIB was markedly increased by amino acid starvation. "
10/01/1989 - "However, using a different approach, that is, amino acid starvation followed by incubation with 10 mM meAIB and transfer to an amino acid-free medium with or without cycloheximide supplementation, a clear increase in AIB uptake, due both to derepression and a release from transinhibition, was observed. "
08/01/1996 - "Thus, while [11C]MeAIB might be useful as a PET radiotracer of System A transport per se, this compound may be limited in its ability to provide measurements of tumor growth rate."
03/01/1994 - "The Na(+)-dependent transport of the System A analog MeAIB was also increased, but only in rats with large tumors. "
01/01/1996 - "MeAIB treatment of tumor cells selectively increased the activities of key invasion-associated type IV collagenases/gelatinases. "
01/01/1995 - "System N (glutamine), System A (MeAIB), and System y+ (arginine) transport activity were assayed, which allowed the authors to compare differences in tumor-induced rates of transport and the influence of resection on transport activity. "
02/01/1983 - "Differentiation inducers (hexamethylene bisacetamide) and phosphodiesterase inhibitors (theophylline, methylisobutyl xanthine) accelerate the stepdown, but even in the presence of these compounds addition of the tumor promoter 12-0-tetradecanoylphorbol-13-acetate (TPA) results in the maintenance of a high level of AIB and meAIB uptake. "
11/01/2012 - "Maternal corticosterone concentrations inversely correlated with materno-fetal MeAIB clearance and fetal weight at D19 but not D16. "
07/01/2012 - "eNOS(-/-) fetal weight and abdominal circumference were significantly reduced compared with WT. Unidirectional maternofetal (14)C-methylaminoisobutyric acid (MeAIB) clearance and sodium-dependent (14)C-MeAIB uptake into mouse placental vesicles were both significantly lower in eNOS(-/-) fetuses, indicating diminished placental nutrient transport. "
01/01/2016 - "Unidirectional (14C)MeAIB transfer per gram placenta (System A amino acid transporter activity) was inversely correlated with fetal weight in [Leu(27)]IGF-II-treated WT animals (P < 0.01). "
|5.||Hepatocellular Carcinoma (Hepatoma)
01/01/1997 - "Insulin-stimulated MeAIB uptake was also inhibited in rat hepatoma cells. "
07/10/1983 - "In the cultured hepatoma cell HTC, amino acid starvation stimulated both influx and efflux of 2-(methylamino)isobutyric acid (MeAIB) across the plasma membrane with little effect on the ultimate cellular accumulation of this amino acid. "
|9.||Amino Acid Transport System A
|10.||Amino Acid Transport Systems (Amino Acid Transporter)