des-Asp(1)-des-Arg(2)-Ile(5)- angiotensin II

3-8 hexapeptide fragment of angiotensin II; smallest potent angiotensin II antagonist

Also Known As:

angiotensin II, des-Asp(1)-des-Arg(2)-Ile(5)-; (A)II(3-8); 1-de-Asp-2-de-Arg-5-Ile-angiotensin II; Nle-AngIV; angiotensin II (3-8); angiotensin II, des-aspartyl(1)-des-arginyl(2)-isoleucine(5)-; angiotensin IV; human angiotensin IV

Networked: 58 relevant articles (4 outcomes, 5 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chai, Siew Yeen: 7 articles (04/2012 - 03/2003)
2.	Albiston, Anthony L: 5 articles (04/2012 - 03/2003)
3.	Hamel, Edith: 4 articles (10/2020 - 01/2017)
4.	Royea, Jessika: 4 articles (10/2020 - 01/2017)
5.	Huang, Eagle Yi-Kung: 3 articles (01/2018 - 07/2012)
6.	De Bundel, Dimitri: 3 articles (03/2010 - 08/2006)
7.	Michotte, Yvette: 3 articles (03/2010 - 08/2006)
8.	Smolders, Ilse: 3 articles (03/2010 - 08/2006)
9.	Martínez-Martos, J M: 2 articles (01/2021 - 01/2013)
10.	Ramírez-Expósito, M J: 2 articles (01/2021 - 01/2013)

Related Diseases

1.	Brain Ischemia (Cerebral Ischemia) 04/10/2012 - "Recent studies have demonstrated that angiotensin IV (Ang IV) provides protection against brain injury caused by cerebral ischemia. "
2.	Brain Injuries (Brain Injury) 04/10/2012 - "Recent studies have demonstrated that angiotensin IV (Ang IV) provides protection against brain injury caused by cerebral ischemia. "
3.	Cardiovascular Diseases (Cardiovascular Disease) 01/01/2007 - "The regulation of the inflammatory response through nuclear factor-kappab pathway by angiotensin IV extends the role of the renin angiotensin system in cardiovascular diseases." 11/15/2023 - "Angiotensin IV (Ang IV) has multiple protective effects against cardiovascular diseases, including diabetic cardiomyopathy and myocardial infarction, but its role in DOX-induced cardiotoxicity is currently unclear. " 01/01/2018 - "Other peptides like angiotensin (1-9), angiotensin (1-7), alamandine and angiotensin IV also help in protecting from cardiovascular diseases by binding to their respective receptors."
4.	Diabetic Cardiomyopathies 01/01/2021 - "Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis." 11/15/2023 - "Angiotensin IV (Ang IV) has multiple protective effects against cardiovascular diseases, including diabetic cardiomyopathy and myocardial infarction, but its role in DOX-induced cardiotoxicity is currently unclear. " 01/01/2021 - "Rationale: The rennin-angiotensin-aldosterone system (RAAS) plays a critical role in the pathogenesis of diabetic cardiomyopathy, but the role of a member of RAAS, angiotensin IV (Ang IV), in this disease and its underlying mechanism are unclear. "
5.	Myocardial Infarction 01/01/2021 - "Continuous Infusion of Angiotensin IV Protects against Acute Myocardial Infarction via the Inhibition of Inflammation and Autophagy." 11/15/2023 - "Angiotensin IV (Ang IV) has multiple protective effects against cardiovascular diseases, including diabetic cardiomyopathy and myocardial infarction, but its role in DOX-induced cardiotoxicity is currently unclear. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	Phospholipid Hydroperoxide Glutathione Peroxidase
3.	Insulin (Novolin)
4.	Aminopeptidases
5.	Angiotensin II
6.	Peptides (Polypeptides)
7.	Angiotensins
8.	angiotensin I (1-7)
9.	Angiotensin III
10.	Scopolamine (Hyoscine)

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Aftercare (After-Treatment)