|1.||Ait-Ghezala, Ghania: 5 articles (01/2015 - 11/2011)|
|2.||Paris, Daniel: 5 articles (01/2015 - 11/2011)|
|3.||Beaulieu-Abdelahad, David: 5 articles (01/2015 - 11/2011)|
|4.||Crawford, Fiona: 5 articles (01/2015 - 11/2011)|
|5.||Mullan, Michael: 4 articles (01/2015 - 11/2011)|
|6.||Verma, Megha: 3 articles (01/2015 - 01/2013)|
|7.||Lanier, Ryan K: 3 articles (01/2014 - 01/2013)|
|8.||Cohen, Amy E: 3 articles (01/2014 - 01/2013)|
|9.||Bachmeier, Corbin: 3 articles (01/2013 - 11/2011)|
|10.||Li, Rena: 2 articles (01/2015 - 01/2015)|
|1.||Arthralgia (Joint Pain)
01/01/2013 - "Mean scores of joint pain and stiffness were significantly (P < 0.0001) reduced after starting anatabine supplementation, and for most respondents joint pain was virtually eliminated. "
01/01/2013 - "The purpose of this internet-based survey study was to provide more information about anatabine users who report benefits for joint pain or stiffness. "
01/01/2013 - "Effects of dietary supplementation with the solanaceae plant alkaloid anatabine on joint pain and stiffness: results from an internet-based survey study."
01/01/2013 - "Around 90% of all individuals rated the effect of anatabine supplementation as good or excellent for joint pain, stiffness, functionality, and overall effects. "
01/01/2013 - "Of the 282 survey respondents, 232 (82%) reported a benefit from anatabine supplementation for one or more joint pain conditions, most commonly the knee, wrists/hands/fingers, shoulder, and back, most often due to osteoarthritis or injury to the joint. "
|2.||Autoimmune Thyroiditis (Lymphomatous Thyroiditis)
09/01/2012 - "Anatabine ameliorates experimental autoimmune thyroiditis."
09/01/2012 - "In this study we tested anatabine, another tobacco alkaloid, in a model of experimental autoimmune thyroiditis. "
09/01/2012 - "Experimental autoimmune thyroiditis was induced by different doses of thyroglobulin, to produce a disease of low, moderate, or high severity, in 88 CBA/J female mice: 43 drank anatabine supplemented water and 45 regular water. "
09/01/2012 - "Finally, anatabine suppressed in a dose-dependent manner macrophage production of inducible nitric oxide synthase and cyclooxygenase 2. Anatabine ameliorates disease in a model of autoimmune thyroiditis, making the delineation of its mechanisms of action and potential clinical utility worthwhile."
|3.||Alzheimer Disease (Alzheimer's Disease)
01/01/2015 - "We therefore investigated the effects of a chronic oral treatment with anatabine in a transgenic mouse model (Tg PS1/APPswe) of Alzheimer's disease (AD) which displays pathological Aβ deposits, neuroinflammation and behavioral deficits. "
01/01/2015 - "Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD."
01/01/2015 - "Correction: Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD."
01/05/2013 - "We also investigated the impact of anatabine on neuroinflammation using a transgenic mouse model of Alzheimer's disease (Tg APPsw) that displays elevated cytokine levels in the brain. "
11/30/2011 - "In vivo, we show that an acute treatment with anatabine for four days significantly lowers brain soluble Aβ₁₋₄₀ and Aβ₁₋₄₂ levels in a transgenic mouse model of Alzheimer's disease. "
01/01/2014 - "Further studies are warranted to determine the longer-term effects and possible actions of anatabine on the course of Hashimoto's thyroiditis."
01/01/2014 - "The effects of anatabine in patients with Hashimoto's thyroiditis were studied. "
01/01/2014 - "Anatabine, an alkaloid found in Solanaceae plants including tobacco, has been reported to ameliorate a mouse model of Hashimoto's thyroiditis. "
09/01/2012 - "The median thyroiditis severity was 0.5 and 2.0 in anatabine and controls, respectively (P = 0.0007 by Wilcoxon rank sum test). "
09/01/2012 - "Anatabine reduced the incidence and severity of thyroiditis in the moderate disease category: only 13 of 21 mice (62%) developed thyroid infiltrates when drinking anatabine as compared with 22 of 23 (96%) controls (relative risk 0.59, P = 0.0174). "
01/05/2013 - "We assessed anatabine's anti-inflammatory activity in vivo using an acute model of inflammation by challenging wild-type mice with LPS. "
04/05/2014 - "Future studies are needed to examine the effects of anatabine on naturally-occurring inflammation that is common with aging or obesity. "
04/05/2014 - "Effects of anatabine and unilateral maximal eccentric isokinetic muscle actions on serum markers of muscle damage and inflammation."
|1.||Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)
|2.||Cyclooxygenase 2 (Cyclooxygenase-2)
|3.||Amyloid (Amyloid Fibrils)
|7.||Biological Markers (Surrogate Marker)