(+,- )- 1- cyclohexyl- 4- (1,2- diphenylethyl)piperazine

RN given refers to (+-)-isomer; structure

Also Known As:

MT 45; MT-45; MT-45, (R)-isomer; MT-45, (S)-isomer; MT-45, dihydrochloride; MT-45, dihydrochloride, (+-)-isomer; MT-45, dihydrochloride, (R)-isomer; MT-45, dihydrochloride, (S)-isomer

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperazines: 26
    - (+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine: 5

Experts

1.	Arfè, R: 1 article (01/2020)
2.	Azevedo, N J: 1 article (01/2020)
3.	Bilel, S: 1 article (01/2020)
4.	Calò, G: 1 article (01/2020)
5.	De-Giorgio, F: 1 article (01/2020)
6.	Frisoni, P: 1 article (01/2020)
7.	Gregori, A: 1 article (01/2020)
8.	Marti, M: 1 article (01/2020)
9.	Neri, M: 1 article (01/2020)
10.	Serpelloni, G: 1 article (01/2020)

Related Diseases

1.	Poisoning 09/11/2014 - "We present clinical data from 12 analytically confirmed hospital cases of MT-45 poisoning. " 09/01/2014 - "MT-45 should be added to the growing list of harmful NPS causing life-threatening poisonings, and rapid actions taken to make it a controlled substance."
2.	Hearing Loss (Hearing Impairment) 09/01/2014 - "MT-45, a new psychoactive substance associated with hearing loss and unconsciousness."
3.	Unconsciousness (Loss of Consciousness) 09/11/2014 - "The cases demonstrate that MT-45, like other opioids, can induce potentially life threatening respiratory depression and loss of consciousness in users and that symptoms are usually reversed by standard doses of the opioid receptor antagonist naloxone. "
4.	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/01/2015 - "There were user reports of MT-45 being used in heroin withdrawal and of 'withdrawal symptoms' after use, suggesting that long-term use may be associated with dependency as seen with other opioids. "
5.	Respiratory Insufficiency (Respiratory Failure) 09/11/2014 - "The cases demonstrate that MT-45, like other opioids, can induce potentially life threatening respiratory depression and loss of consciousness in users and that symptoms are usually reversed by standard doses of the opioid receptor antagonist naloxone. "

Related Drugs and Biologics

1.	Opioid Analgesics (Opioids)
2.	Controlled Substances
3.	Opioid Receptors (Opioid Receptor)
4.	Narcotic Antagonists (Opioid Antagonists)
5.	Naloxone (Narcan)
6.	Morphine (MS Contin)
7.	Heroin (Diamorphine)
8.	Piperazine