dimemorfan (AT 17)

RN given refers to parent cpd without isomeric designation; synonym At 17 refers to phosphate[1:1] salt; structure

Also Known As:

AT 17; Astomin; Dastosin; d-3-methyl-N-methylmorphinan; dimemorfan phosphate; dimemorfan phosphate (1:1) salt; dimemorfan, (9alpha,13alpha,14alpha)-isomer; dinemorphan; 3,17-dimethylmorphinan

Networked: 1412 relevant articles (35 outcomes, 95 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chen, Chih-Ping: 16 articles (07/2022 - 01/2006)
2.	Wang, Wayseen: 16 articles (07/2022 - 01/2006)
3.	Chern, Schu-Rern: 13 articles (07/2022 - 06/2010)
4.	Chen, Shin-Wen: 10 articles (07/2022 - 02/2017)
5.	Wu, Peih-Shan: 7 articles (03/2022 - 02/2017)
6.	Wu, Fang-Tzu: 6 articles (07/2022 - 09/2019)
7.	Beilin, Lawrence J: 6 articles (01/2022 - 01/2013)
8.	Mori, Trevor A: 5 articles (01/2022 - 05/2013)
9.	Lee, Chen-Chi: 4 articles (07/2022 - 02/2018)
10.	Oddy, Wendy H: 4 articles (01/2022 - 05/2013)

Related Diseases

1.	Pain (Aches) 10/01/2017 - "Methods Data from 1088 participants (52.1% female) with "no LBP," "LBP with minimal impact," and "LBP with impact" at 17 years of age and a range of measures from multiple domains, including spinal pain, physical, psychological, social, and lifestyle, at 14 years of age were collected for the study. " 01/01/2021 - "A pragmatic, multicentre parallel group randomized controlled trial at 17 National Health Service (NHS) hospital departments recruited adults with symptomatic BTOA and at least moderate hand pain and dysfunction. " 06/01/2016 - "At 17 days post operation, the patient presented to the emergency room complaining of left leg swelling and sharp, shooting pain radiating down her left leg. " 01/01/2016 - "However, anxiety at 13 was significantly associated with pain-related anxiety at 17 (n = 1831). " 01/01/2016 - "Anxiety at 13 and its effect on pain, pain-related anxiety, and pain-related disability at 17: An ALSPAC cohort longitudinal analysis."
2.	Infections 11/15/2016 - "First, the recovery rates of the intestinal worms and female fecundity were determined, and the results showed that the intestinal worms were completely eliminated at 17 days post-infection (dpi) and that large numbers of new-born larvae (NBL) were generated from 5 to 9dpi. " 01/01/2021 - "The qPCR results showed that the infection intensity of Haemaphysalis longicornis larvae and nymphs was not constant over the sampling period, and after initially dropping after molting to nymphs, it then rose with fasting to a maximum at 17 and 23 wk post-feeding. " 08/20/2020 - "The first deaths of shrimp challenged with Vp M0904 occurred 4 h post-infection (hpi), reached 50% mortality at 17 hpi, and showed more acute pathological progression associated with AHPND despite both strains having similar bacterial densities from 0-4 hpi. " 12/01/2018 - "In 2010-2017, ARV infection was found in birds from 81 flocks of broiler chickens and/or layers, 8 flocks of slaughter turkeys, and in 4 hatchery embryos at 17-20 days of incubation. " 10/01/2018 - "Symptoms were reviewed in CrAg-positive patients identified by screening 19233 individuals with human immunodeficiency virus infection and CD4 cell counts <100/µL at 17 clinics and 3 hospitals in Johannesburg from September 2012 until September 2015, and at 2 hospitals until June 2016. "
3.	Neoplasms (Cancer) 11/01/2021 - "Participants were adult patients with metastatic solid tumors who were undergoing oncological care and for whom an oncologist would agree with the statement "would not be surprised if the patient died in the next year." The trial was conducted at 17 community oncology practices in western Pennsylvania. " 09/01/2021 - "This prospective real-world study was conducted at 17 major cancer centers in Sichuan, China. " 01/01/2021 - "We did a randomised, open-label, phase 3 trial at 17 cancer centres in France. " 09/01/2012 - "Based on a robust response, several of our protocols for Tg.rasH2 studies with 15 mice/sex and terminal sacrifice at 17 ± 1 weeks were submitted and accepted by the Carcinogenicity Assessment Committee of the US Food and Drug Administration since we demonstrated close to 100% response for the development of lung and splenic tumors (target organs) in 500 mice/sex. " 10/18/2023 - "The outcomes were incident cancer at 17 sites and all cancers combined. "
4.	Wounds and Injuries (Trauma) 07/31/2021 - "When comparing the impacts at 21 °C (present study) and 17 °C (previously published data), organisms exposed to remediated seawater at a higher temperature presented higher injuries than organisms at 17 °C. " 10/01/1995 - "This study reports on the experience in the treatment of such injuries at 17 urological and surgical institutions." 01/01/2023 - "Implementation of the PQI to evaluate the strength of injury prevention action plans and make recommendations for quality improvement to drive reductions in injuries at 17 Army installations. " 03/01/2021 - "A retrospective national multicenter study was performed including all patients admitted for renal trauma at 17 hospitals between 2005 and 2015. " 04/01/2020 - "A retrospective national multicenter study was conducted including all patients who presented with renal trauma at 17 hospitals between 2005 and 2015. "
5.	Fibrosis (Cirrhosis) 01/01/2022 - "Cardiac fibrosis, inflammatory cell infiltration, and gene expression were determined at 17 weeks. " 10/01/2020 - "Inactivation of Pkhd1 beginning at 4 weeks of age resulted in a polycystic liver phenotype with minimal fibrosis at 17 weeks. " 05/01/1997 - "At 17 days there were ulcerated zones to the muscular layer with fibrosis and cellular rests at tracheal path. " 01/01/1990 - "Myocardial biopsy at 17 years of age disclosed a normal endocardium and marked interstitial fibrosis of the myocardium. " 06/01/2015 - "In some animals TGF-β injections were stopped at 17 d when TM fibrosis and IOP were consistently raised and either hrDecorin or PBS IC injections were administered between 21 d and 30 d. "

Related Drugs and Biologics

1.	Blood Glucose (Blood Sugar)
2.	Amyloid beta-Peptides
3.	Scopolamine (Hyoscine)
4.	alpha-Fetoproteins (alpha-Fetoprotein)
5.	Glutamic Acid (Glutamate)
6.	Vincristine (Oncovin)
7.	Isoproterenol (Isoprenaline)
8.	1-phenyl-3,3-dimethyltriazene (PDT)
9.	Octreotide (Sandostatin)
10.	Thioguanine (Tioguanine)

Related Therapies and Procedures

1.	Osteotomy
2.	Distraction Osteogenesis
3.	Therapeutics
4.	Drug Therapy (Chemotherapy)
5.	Stents