|1.||Wen, Hsiao-Chuan: 3 articles (01/2013 - 03/2011)|
|2.||Liao, May-Hua: 3 articles (01/2013 - 03/2011)|
|3.||Lee, Ming-Yi: 2 articles (01/2013 - 03/2011)|
|4.||Chang, Li-Hsueh: 1 article (01/2013)|
|5.||Tsai, Yuan-Nuan: 1 article (01/2013)|
|6.||Juang, Chi-Long: 1 article (01/2013)|
|7.||Yang, Chi-Yu: 1 article (01/2013)|
|8.||Lin, Wen-Chieh: 1 article (04/2011)|
|9.||Pu, Hsiao-Fung: 1 article (04/2011)|
|10.||Tsai, Yung-Nuan: 1 article (03/2011)|
|1.||Glioblastoma (Glioblastoma Multiforme)
04/01/2011 - "These findings suggested that TD extract and tagitinin C were effective for treating malignant glioblastoma."
04/01/2011 - "Our results suggested that tagitinin C was the main component in viability inhibition on malignant glioblastoma cells, and also accounted to be the most abundant component (>65%) in TD extract. "
04/01/2011 - "Tithonia diversifolia and its main active component tagitinin C induce survivin inhibition and G2/M arrest in human malignant glioblastoma cells."
03/23/2011 - "In PARP, p-p38, ULK1, and LC3-II expression, the anti-glioblastoma induced by tagitinin C was likely via autophagy. "
03/23/2011 - "Identification and anti-human glioblastoma activity of tagitinin C from Tithonia diversifolia methanolic extract."
|4.||Hepatocellular Carcinoma (Hepatoma)
01/01/2013 - "diversifolia (TDM) and tagitinin C were found to have cytotoxic activities against human hepatoma Hep-G2 cells in the MTT assay with IC(50) values of 40.0 ± 2.0 and 2.0 ± 0.1 μg/mL, respectively. "
01/01/2013 - "The high morbidity and mortality rate of hepatoma in Taiwan motivated our interest in the investigation of tagitinin C's mechanism against the human hepatocellular carcinoma. "
01/01/2013 - "Anti-human hepatoma Hep-G2 proliferative, apoptotic, and antimutagenic activity of tagitinin C from Tithonia diversifolia leaves."
|5.||Colonic Neoplasms (Colon Cancer)
04/01/2002 - "Activity-guided fractionation of an ethyl acetate extract of the aerial parts of Tithonia diversifolia, using an antiproliferation bioassay performed with human colon cancer (Col2) cells, led to the isolation of three new sesquiterpenoids, 2alpha-hydroxytirotundin (1), tithofolinolide (2), and 3alpha-acetoxydiversifolol (3), along with eight known sesquiterpene lactones, 3beta-acetoxy-8beta-isobutyryloxyreynosin (4), tagitinin C (5), 1beta,2alpha-epoxytagitinin C (6), 4alpha,10alpha-dihydroxy-3-oxo-8beta-isobutyryloxyguaia-11(13)-en-12,6alpha-olide (7), 3alpha-acetoxy-4alpha-hydroxy-11(13)-eudesmen-12-oic acid methyl ester, 17,20-dihydroxygeranylnerol, tagitinin A, and tirotundin. "
|3.||Nitric Oxide (Nitrogen Monoxide)