|1.||Lee, Su-Jae: 5 articles (01/2007 - 02/2003)|
|2.||Lee, Yun-Sil: 4 articles (01/2007 - 02/2003)|
|3.||Chung, Hee Yong: 4 articles (01/2007 - 12/2003)|
|4.||Park, Moon-Taek: 4 articles (01/2007 - 02/2003)|
|5.||Choi, Jung-A: 3 articles (02/2005 - 02/2003)|
|6.||Kang, Chang-Mo: 3 articles (02/2005 - 02/2003)|
|7.||Bae, Sangwoo: 3 articles (02/2005 - 02/2003)|
|8.||Cho, Chul-Koo: 3 articles (02/2005 - 02/2003)|
|9.||Kang, Seongman: 3 articles (02/2005 - 02/2003)|
|10.||Kim, Min-Jung: 2 articles (01/2007 - 02/2005)|
06/01/2007 - "Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris."
01/04/2010 - "Phytosphingosine (PS) is a promising compound in skin formulations, considering its application in the treatment of acne and different inflammations as well as in the 'anti age' cosmetics. "
02/01/2015 - "Cosmetics with antimicrobial and anti-inflammatory substances such as, respectively, ethyl lactate or phytosphingosine and nicotinamide or resveratrol, may speed acne recovery. "
01/01/2007 - "These findings support the potential application of combination treatment with TRAIL and phytosphingosine in the treatment of cancers that are less sensitive to TRAIL."
01/01/2007 - "We explored whether TRAIL in combination with phytosphingosine could sensitize cancer cells to TRAIL. "
01/01/2007 - "Phytosphingosine in combination with TRAIL sensitizes cancer cells to TRAIL through synergistic up-regulation of DR4 and DR5."
02/15/2005 - "Taken together, these results demonstrate that enhancement of cell death of radiation-resistant cancer cells by phytosphingosine treatment in combination with gamma-radiation is mediated by nuclear translocation of AIF, which is in turn mediated both by ROS-dependent Bax relocalization and ROS-independent PARP-1 activation. "
02/15/2005 - "Phytosphingosine in combination with ionizing radiation enhances apoptotic cell death in radiation-resistant cancer cells through ROS-dependent and -independent AIF release."
01/01/2010 - "This study evaluated the cytotoxic effects and underlying mechanisms of action of novel phytosphingosine derivatives, including N-monomethylphytosphingosine (MMPH) and N,N-dimethylphytosphingosine (DMPH) and the pegylated forms MMPH-PEG and DMPH-PEG, in human leukemia HL60 cells. "
08/01/2010 - "Previously, we introduced a novel phytosphingosine derivative, N,N-dimethyl phytosphingosine (DMPS), as a potent anticancer therapeutic agent in human leukemia cells. "
01/01/2010 - "Cytotoxic effects of novel phytosphingosine derivatives, including N,N-dimethylphytosphingosine and N-monomethylphytosphingosine, in human leukemia cell line HL60."
01/01/2007 - "These results indicate that phytosphingosine in combination with As(2)O(3) induces synergistic apoptosis in As(2)O(3)-resistant leukemia cells through the p38 MAPK-mediated mitochondrial translocation of Bax and the PARP-1 activation, and that p38 MAPK and PARP-1 activations are reactive oxygen species dependent. "
|5.||T-Cell Lymphoma (Lymphoma, T Cell)
02/01/2005 - "In the present study, we examined the phytosphingosine-induced apoptosis mechanism, focusing on mitochondria in human T-cell lymphoma Jurkat cells. "
02/15/2005 - "Here, we showed that phytosphingosine treatment in combination with gamma-radiation enhanced apoptotic cell death of radiation-resistant human T-cell lymphoma in a caspase-independent manner. "
|2.||Cytochromes c (Cytochrome c)
|3.||Mitogen-Activated Protein Kinases
|7.||Caspase 8 (Caspase-8)
|8.||p38 Mitogen-Activated Protein Kinases
|9.||Biological Markers (Surrogate Marker)