hydroperoxyisophosphamide

RN given refers to parent cpd without isomeric designation

Also Known As:

4-hydroperoxyifosfamide; hydroperoxyisophosphamide, (cis)-isomer; hydroperoxyisophosphamide, (trans)-isomer; NSC-227114

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Blicharski, Kamil: 1 article (11/2017)
2.	Fedoročko, Peter: 1 article (11/2017)
3.	Mazur, Lidia: 1 article (11/2017)
4.	Mikeš, Jaromir: 1 article (11/2017)
5.	Niemeyer, Ulf: 1 article (11/2017)
6.	Opydo-Chanek, Malgorzata: 1 article (11/2017)
7.	Śladowska, Katarzyna: 1 article (11/2017)
8.	Bruheim, Skjalg: 1 article (12/2009)
9.	Fodstad, Oystein: 1 article (12/2009)
10.	Ju, Jingfang: 1 article (12/2009)

Related Diseases

1.	Gliosarcoma 12/01/2001 - "The present study investigates the cytotoxic events induced by CPA in 9L gliosarcoma cells retrovirally transduced with CYP2B6, or induced in wild-type 9L cells treated with mafosfamide (MFA) or 4-hydroperoxyifosfamide (4OOH-IFA), chemically activated forms of CPA and its isomer ifosfamide. "
2.	Glioma (Gliomas) 01/01/1993 - "In vitro studies on interaction of 4-hydroperoxyifosfamide and 2-mercaptoethanesulphonate in malignant gliomas." 01/01/1993 - "Glioma cell cultures were treated in monolayer 96-well tissue-culture plates for 2 h each, with 4-hydroperoxyifosfamide and MESNA combined in both sequences, or alone. "
3.	Osteosarcoma (Osteogenic Sarcoma) 12/01/2009 - "Finally, small interfering RNA-mediated gene silencing of IER3 and S100A2 sensitized the human osteosarcoma cell line OHS to treatment with 4-hydroperoxyifosfamide. " 05/01/1995 - "Methylglyoxal bis (cyclopentylamidinohydrazone) (MGBCP): antitumor effect against human osteosarcoma cells and combined effect with methotrexate, adriamycin and 4-hydroperoxyifosfamide."
4.	Testicular Neoplasms (Testicular Cancer) 12/31/1985 - "The effect of CCNU, chlorambucil, cisplatin, melphalan, prednimustine, procarbazine and the pro-active derivatives of cyclophosphamide and ifosfamide, 4-hydroperoxycyclophosphamide and 4-hydroperoxyifosfamide, was tested on non-Hodgkin lymphomas, germ cell testicular tumors, breast and ovarian cancers. "
5.	Ovarian Neoplasms (Ovarian Cancer) 12/31/1985 - "The effect of CCNU, chlorambucil, cisplatin, melphalan, prednimustine, procarbazine and the pro-active derivatives of cyclophosphamide and ifosfamide, 4-hydroperoxycyclophosphamide and 4-hydroperoxyifosfamide, was tested on non-Hodgkin lymphomas, germ cell testicular tumors, breast and ovarian cancers. "

Related Drugs and Biologics

1.	Ifosfamide
2.	Cytochrome P-450 CYP2B6 (CYP2B6)
3.	mafosfamide
4.	perfosfamide
5.	Small Interfering RNA (siRNA)
6.	Mesna (Coenzyme M)
7.	Solutions
8.	Procarbazine (Matulane)
9.	Prednimustine
10.	Methotrexate (Mexate)