higenamine (norcoclaurine)

Subscribe to Selected New Research on higenamine

15 relevant articles (1 outcomes, 3 trials/studies) found for this Bio-Agent

Description: structure; RN given refers to (+-)-isomer

Also Known As:

norcoclaurine; 1(S)-norcoclaurine; 1-(p-hydroxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; O-demethylcoclaurine; higenamine hydrobromide, (+-)-isomer; higenamine hydrochloride, (S)-isomer; higenamine oxalate (1:1), (+-)-isomer; higenamine, tartrate (1:1), R-(R*,R*)-(+-)-isomer

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 23

Alkaloids: 633

higenamine: 15

2-Ring Heterocyclic Compounds

Isoquinolines: 17

Tetrahydroisoquinolines: 33

higenamine: 15

Experts

1.	Chang, Ki Churl: 4 articles (07/2008 - 04/2002)
2.	Yun-Choi, Hye Sook: 3 articles (07/2008 - 04/2002)
3.	Pyo, Mi Kyung: 2 articles (07/2008 - 04/2002)
4.	Lee, Young Soo: 2 articles (07/2006 - 02/2006)
5.	Seo, Han Geuk: 2 articles (07/2006 - 02/2006)
6.	Lee, Jae Heun: 2 articles (07/2006 - 02/2006)
7.	Kim, Hye Jung: 2 articles (07/2006 - 02/2006)
8.	Kang, Young Jin: 2 articles (07/2006 - 02/2006)
9.	Park, Min Kyu: 2 articles (07/2006 - 02/2006)
10.	Kim, Doo-Hyun: 1 article (07/2008)

Related Diseases

1.	Septic Shock (Toxic Shock Syndrome) 10/01/1999 - "Furthermore, due to positive inotropic action, higenamine may be more effective in a condition where myocardial contractility is likely to depress, such as in septic shock and/or endotoxin-induced inflammatory disorders." 02/01/2006 - "Taken together, it was concluded that (S)-higenamine may be more beneficial than (R)-enantiomer in diseases associated with iNOS over-expression, such as septic shock." Get all the results and reference details, order at left...
2.	Bradycardia 06/01/1980 - "Effects of acute administration of higenamine on bradyarrhythmias: a preliminary clinical study (author's transl)]" 10/01/1982 - "Effect of acute higenamine administration on bradyarrhythmias and HIS bundle" 10/01/1995 - "Although higenamine (100 micrograms/kg, i.p.), a beta 1-adrenergic agonist (a compound derived from aconite), had no effect per se, it inhibited aconitine (another compound derived from aconite extract)-induced bradycardia within 30 s of administration in ACh-low sensitive mice but not in ACh-high sensitive mice" 01/01/1985 - "Thus, higenamine seems to be safer than isoproterenol in the treatment of bradyarrhythmias." Get all the results and reference details, order at left...
3.	Coronary Stenosis (Coronary Artery Stenosis) 05/01/2005 - "CONCLUSION: Our study demonstrates that detection of coronary artery stenosis and ischemic myocardium by myocardial perfusion imaging with higenamine is highly sensitive." Get all the results and reference details, order at left...
4.	Sick Sinus Syndrome 01/01/1984 - "Clinical electrophysiological studies of higenamine in sick sinus syndrome]" Get all the results and reference details, order at left...
5.	Tachycardia (Tachyarrhythmias) 01/01/1985 - "The above facts suggest that: (1) higher concentration of higenamine may induce tachyarrhythmias, while lower concentration may prevent arrhythmias; (2) in low concentration of higenamine, there is a relative increase of ERP" 09/01/1994 - "These results indicate that higenamine is a beta 1-adrenoceptor full agonist in murine atria and that the aconitine-induced tachyarrhythmia is augmented by the beta 1-adrenergic action of higenamine." 09/01/1994 - "Positive chronotropic and inotropic effects of higenamine and its enhancing action on the aconitine-induced tachyarrhythmia in isolated murine atria." 09/01/1994 - "Higenamine (2.5 nM) and dobutamine (1 nM) did not cause chronotropic effects by themselves, but enhanced the aconitine-induced tachyarrhythmia" Get all the results and reference details, order at left...
15 Diseases and 15 more articles analyzed in the Research Interface, order at left...

Related Drugs and Biologics

1.	Dobutamine
2.	Aconitine
3.	Heme Oxygenase-1
4.	Norepinephrine (Noradrenaline)
5.	Isoproterenol (Isoprenaline)
6.	Dacarbazine (DIC)
6 Drugs and Important Bio-Agents and 7 more articles analyzed in the Research Interface, order at left...

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