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polyphenylalanine

RN given refers to (DL)-isomer

Also Known As:

polyphenylalanine, (L)-isomer

Networked: 13 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - polyphenylalanine: 13

Related Diseases

1.	Non-Hodgkin Lymphoma (Lymphosarcoma) 03/24/1972 - "Studies on polyphenylalanine synthesis with a cell-free system of rat lymphosarcoma."
2.	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 08/01/1982 - "Protein synthesis primed by endogenous messenger RNA (mRNA) as well as polyuridylic acid-[poly (U)] directed polyphenylalanine synthesis was measured in extracts of blood lymphocytes from a series of 50 chronic lymphocytic leukemia (CLL) patients and compared with the prognostic stage. " 11/01/1988 - "The activity levels of the enzyme poly(A)polymerase and the levels of protein synthesis primed by endogenous messenger RNA (mRNA) as well as polyuridylic acid, poly(U) directed polyphenylalanine synthesis, were determined in lymphocytic extracts from 17 patients with chronic lymphocytic leukemia of the B cell type. "
3.	Neoplasms (Cancer) 01/01/1978 - "A stimulation of polyphenylalanine synthesis resulted from the addition of cytosols from tumors or host liver to ribosomes from normal rat liver. " 01/01/2023 - "This self-assembled micelle possesses the following essential components for CPT: (1) pH-sensitive PEG (OHC-PEG-CHO) for prolonging blood circulation and allowing biocompatibility by shielding the cationic micelles, which can be detached under the tumor acidic microenvironment and facilitates the cellular uptake; (2) polypeptide polylysine-polyphenylalanine (PKF) synthesized via ring-opening polymerization for micelle formation and CPT analogue loading; (3) dimeric CPT (DCPT) with redox-sensitive linker for increasing CPT loading and ensuring drug release at tumor sites. "
4.	Congenital Structural Myopathies (Centronuclear Myopathy) 12/01/1987 - "Ribosomes isolated from fibroblasts, muscle tissues, and blood cells of a patient with congenital non-progressive myopathy were used for in vitro measurement of protein synthesis in a heterologous poly(U)-directed polyphenylalanine synthesis system. "
5.	Shock 07/15/1980 - "The introduction of 16--100 scissions in the RNA moiety had no effect on the activity of the L-subparticles in polyphenylalanine synthesis, and there was no effect on the stability of L-subparticles to high-salt shock treatment and a marginal effect on the reconstruction of L-subparticles from high-salt-shock core-particles and split-protein fractions. "

Related Drugs and Biologics

1.	Poly U
2.	Proteins (Proteins, Gene)
3.	Messenger RNA (mRNA)
4.	Peptides (Polypeptides)
5.	Peptide Initiation Factors (Initiation Factor)
6.	Acids
7.	Octoxynol (Triton X 100)
8.	Salts
9.	RNA (Ribonucleic Acid)
10.	Polylysine