HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

phosphopantothenic acid

RN given refers to (R)-isomer

Also Known As:

4'-phosphopantothenate; phosphopantothenate; phosphopantothenic acid, calcium salt (2:1); phosphopantothenic acid, calcium salt, (R)-isomer

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Imides: 79
  - Pantothenic Acid: 357
    - phosphopantothenic acid: 7
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Alanine: 4133
    - beta-Alanine: 172
      - Pantothenic Acid: 357
        phosphopantothenic acid: 7

Experts

1.	Di Marco, Annalise: 2 articles (12/2020 - 01/2018)
2.	Elbaum, Daniel: 2 articles (12/2020 - 01/2018)
3.	Harper, Steven: 2 articles (12/2020 - 01/2018)
4.	Monteagudo, Edith: 2 articles (12/2020 - 01/2018)
5.	Chen, Gang: 1 article (01/2021)
6.	Li, Ang: 1 article (01/2021)
7.	Li, Zixuan: 1 article (01/2021)
8.	Sun, Minglei: 1 article (01/2021)
9.	Sun, Qiang: 1 article (01/2021)
10.	Wang, Panpan: 1 article (01/2021)

Related Diseases

1.	Pantothenate Kinase-Associated Neurodegeneration (Hallervorden-Spatz Disease) 12/24/2020 - "Cyclic Phosphopantothenic Acid Prodrugs for Treatment of Pantothenate Kinase-Associated Neurodegeneration." 01/01/2018 - "Fosmetpantotenate (RE-024), a phosphopantothenate replacement therapy for pantothenate kinase-associated neurodegeneration: Mechanism of action and efficacy in nonclinical models." 01/01/2018 - "Fosmetpantotenate is a phosphopantothenic acid prodrug in clinical development for treatment of pantothenate kinase-associated neurodegeneration, which aims to replenish phosphopantothenic acid in patients. " 12/24/2020 - "Mutations in the human PANK2 gene are implicated in neurodegenerative diseases such as pantothenate kinase-associated neurodegeneration (PKAN) and result in low levels of coenzyme-A (CoA) in the CNS due to impaired production of phosphopantothenic acid (PPA) from vitamin B5. "
2.	Decapitation 10/01/2001 - "All the tested substances were administered during the last 10 days before decapitation (i.m., of dosage equivalent to 150 mg/kg body wt of phosphopantothenate). "
3.	Neurodegenerative Diseases (Neurodegenerative Disease) 12/24/2020 - "Mutations in the human PANK2 gene are implicated in neurodegenerative diseases such as pantothenate kinase-associated neurodegeneration (PKAN) and result in low levels of coenzyme-A (CoA) in the CNS due to impaired production of phosphopantothenic acid (PPA) from vitamin B5. "
4.	Weight Loss (Weight Reduction) 09/13/2022 - "Subjects who lost weight after FMT sustained enrichment of Bifidobacterium bifidum and Alistipes onderdonkii in the duodenal, colonic mucosal, and fecal microbiome and increased levels of phosphopantothenate biosynthesis and fecal metabolite eicosapentaenoic acid (EPA), compared with those without weight loss. "
5.	Tuberculosis (Tuberculoses) 07/09/2010 - "tuberculosis enzyme with (1) GMPPCP and pantothenate, (2) GDP and phosphopantothenate, (3) GDP, (4) GDP and pantothenate, (5) AMPPCP, and (6) GMPPCP, reported here, and the structures of the complexes of the two enzymes involving coenzyme A and different adenyl nucleotides reported earlier. "

Related Drugs and Biologics

1.	Coenzyme A (CoA)
2.	Prodrugs
3.	Pantothenic Acid (Calcium Pantothenate)
4.	Eicosapentaenoic Acid
5.	Riboflavin (Vitamin B2)
6.	Nucleotides
7.	Inosine
8.	Guanosine Diphosphate (GDP)
9.	Enzymes
10.	dexpanthenol (panthenol)

Related Therapies and Procedures

1.	Therapeutics