oxetorone

treatment of migraine; RN given refers to parent cpd; structure

Also Known As:

6-(3-dimethylamino-1-propylidene) benzofuro(2,3-e)-12H-benzo(b)oxepine fumarate; Nocertone; oxetorone fumarate; oxetorone fumarate, (E)-isomer

Networked: 13 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzoxepins: 1
      - oxetorone: 13

Experts

1.	Bruneau, Chloé: 1 article (02/2017)
2.	Deguigne, Marie: 1 article (02/2017)
3.	Le Roux, Gaël: 1 article (02/2017)
4.	Touré, Ali: 1 article (02/2017)
5.	Turcant, Alain: 1 article (02/2017)
6.	Azouz, M M: 1 article (02/2010)
7.	Chatti, S: 1 article (02/2010)
8.	Fathallah, N: 1 article (02/2010)
9.	Descotes, Jacques: 1 article (11/2006)
10.	Patat, Anne-Marie: 1 article (11/2006)

Related Diseases

1.	Migraine Disorders (Migraine) 09/05/1978 - "[Clinical study of oxetorone in catamenial migraine. " 08/18/1978 - "[The interval treatment of migraine with nocertone]." 08/01/1978 - "[Double-blind study of oxetorone in patients with migraine or migrainous headache (author's transl)]." 08/01/2004 - "For migraine prophylaxis in adults, the following can be used: propranolol, metoprolol, oxetorone, or amitriptyline as first-line treatment, and pizotifen, flunarizine, valproate sodium, or topiramate as second-line treatment. "
2.	Lymphocytic Colitis 02/01/2010 - "[Lymphocytic colitis associated with oxetorone consumption]." 05/01/2002 - "[Oxetorone-associated lymphocytic colitis]."
3.	Poisoning 11/01/2006 - "[Acute poisoning with oxetorone]." 01/01/1990 - "The authors report a case of severe self-poisoning with oxetorone. " 01/01/1990 - "Severe self-poisoning with oxetorone: report of one case."
4.	Headache (Headaches) 08/17/1976 - "[Double-blind study with oxetorone in cephalalgia (author's transl)]." 08/01/1978 - "[Double-blind study of oxetorone in patients with migraine or migrainous headache (author's transl)]."
5.	Ventricular Tachycardia 02/01/2017 - "Symptoms of moderate severity (PSS2 = drowsiness, hypertonia, myosis, convulsions, arterial hypotension, QRS widening, QTc prolongation) were observed following ingestion of more than 600 mg of oxetorone (median dose =1200 mg) and severe symptoms (PSS 3 = coma, convulsions, QTc prolongation, QRS widening, ventricular tachycardia, arterial hypotension, cardiogenic shock) were observed starting from 1800 mg (median dose =2700 mg). "

Related Drugs and Biologics

1.	Valproic Acid (Depakote)
2.	Propranolol (Inderal)
3.	Pizotyline (BC 105)
4.	Metoprolol (Toprol-XL)
5.	Flunarizine
6.	Amitriptyline (Elavil)
7.	Topiramate (Topamax)