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kryptopyrrole

metabolite in schizophrenia

Also Known As:

2,4-dimethyl-3-ethylpyrrole

Networked: 9 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrroles: 369
      - kryptopyrrole: 9

Related Diseases

1.	Hepatic Porphyrias (Hepatic Porphyria) 05/01/1976 - "The porphyrinogenic effects of kryptopyrrole in the rat and the occurrence of urinary kryptopyrrole in human hereditary hepatic porphyria." 05/01/1976 - "2. Kryptopyrrole was present in the urine of patients with hereditary hepatic porphyria, in attack and in remission, but not in those with latent porphyria." 01/01/1979 - "The concentration of kryptopyrrole required for 50% inhibition of a maximum twitch tension (ID50) was 0.085 mM. 3 Oxidation products of kryptopyrrole with chromatographic properties similar to those of urinary constituents reported in schizophrenia and hepatic porphyrias had little or no effect at similar concentrations. "
2.	Porphyrias (Porphyria) 05/01/1976 - "2. Kryptopyrrole was present in the urine of patients with hereditary hepatic porphyria, in attack and in remission, but not in those with latent porphyria."
3.	Acute Intermittent Porphyria (Porphyria, Acute) 12/02/1972 - "Kryptopyrrole-like substance in acute intermittent porphyria." 02/01/1978 - "No hemopyrrole or kryptopyrrole could be detected in 52 samples, from 17 controls, 29 schizophrenics, and six persons with acute intermittent porphyria."
4.	Schizophrenia (Dementia Praecox) 01/01/1979 - "The concentration of kryptopyrrole required for 50% inhibition of a maximum twitch tension (ID50) was 0.085 mM. 3 Oxidation products of kryptopyrrole with chromatographic properties similar to those of urinary constituents reported in schizophrenia and hepatic porphyrias had little or no effect at similar concentrations. " 01/01/1973 - "Biochemical relationship between kryptopyrrole (mauve factor and trans-3-methyl-2-hexenoic acid (schizophrenia odor)."
5.	Psychotic Disorders (Schizoaffective Disorder) 03/01/1975 - "Kryptopyrrole causes major central nervous system dysfunction, and these findings are discussed in the context of a drug-induced model of psychoses." 11/22/1969 - "Identification of kryptopyrrole in human urine and its relation to psychosis."

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