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immunoregulatory alpha globulin

immunosuppressive peptide in human serum

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        immunoregulatory alpha globulin: 6
  - Globulins: 3062
    - Serum Globulins: 553
      - Alpha-Globulins: 100
        immunoregulatory alpha globulin: 6

Related Diseases

1.	Wounds and Injuries (Trauma) 01/01/1977 - "By size and activity the trauma serum factor resembled immunoregulatory alpha globulin, a naturally-occurring serum inhibitor of T-lymphocyte reactions. "
2.	Sarcoma (Soft Tissue Sarcoma) 09/01/1979 - "The PHA-colchicine assay was successfully used to quantify inhibition by normal plasma, normal mouse sera, mouse neonate sera, murine Ehrlich's and sarcoma I ascitic fluids and an immunoregulatory alpha-globulin peptide preparation. "
3.	Neoplasms (Cancer) 09/01/1977 - "The suppression of tumor-specific cell-mediated cytotoxicity by human immunoregulatory alpha-globulin (IRA), by a peptide fraction derived from IRA, and by IRA-like peptides from the serum of cancer patients was studied in a syngeneic murine tumor-host system. " 09/01/1977 - "Suppression of tumor-specific cell-mediated cytotoxicity by immunoregulatory alpha-globulin and by immunoregulatory alpha-globulin-like peptides from cancer patients."
4.	Lymphoma (Lymphomas) 12/01/1974 - "Effect of immunoregulatory alpha-globulin on in vitro proliferative response of immune rat lymphocytes to syngeneic Gross virus-induced lymphoma."
5.	Leukemia 12/01/1975 - "Immunoregulatory alpha-globulin (IRA) derived from normal human plasma decreased cytotoxic reactivity as measured by an in vitro 5-iodo-2'-deoxyridine release assay of immune mouse lymphocytes against the syngeneic Friend virus-induced leukemia, FBL-3. " 12/01/1975 - "In vitro inhibition of cell-mediated cytotoxicity against syngeneic Friend virus-induced leukemia by immunoregulatory alpha globulin."

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Immunoglobulin M (IgM)
3.	Immunoglobulin G (IgG)
4.	Colchicine