|1.||Godley, Lucy A: 6 articles (07/2015 - 09/2011)|
|2.||Murphy, George F: 5 articles (11/2015 - 09/2012)|
|3.||Vasanthakumar, Aparna: 5 articles (07/2015 - 09/2011)|
|4.||Zhan, Qian: 4 articles (11/2015 - 09/2012)|
|5.||Madzo, Jozef: 4 articles (07/2015 - 01/2013)|
|6.||Xu, Shuyun: 3 articles (11/2015 - 02/2015)|
|7.||Mihm, Martin C: 3 articles (11/2015 - 09/2012)|
|8.||Lian, Christine Guo: 3 articles (11/2015 - 09/2012)|
|9.||Lin, Li: 3 articles (10/2015 - 07/2013)|
|10.||Jin, Peng: 3 articles (10/2015 - 07/2013)|
08/14/2014 - "In this study, we measured 5-hydroxymethylcytosine (5hmC) levels in 206 clinically and molecularly well-characterized younger adult AML patients (≤60 years) included in the European Organization for Research and Treatment of Cancer/Gruppo Italiano Malattie Ematologiche dell'Adulto (EORTC/GIMEMA) AML-12 06991 clinical trial and correlated the 5hmC levels with mutational status and overall survival (OS). "
07/01/2014 - "This study further substantiates the association of 5-hydroxymethylcytosine loss with dysplastic cytomorphologic features and tumor progression and supports the classification of borderline lesions as a biologically distinct category of melanocytic lesions."
01/01/2014 - "In the context of current epigenetic therapies and by using recent functional studies, we propose plausible mechanisms to target the 5-hydroxymethylcytosine pathway in cancer. "
11/01/2015 - "Here, we investigated 170 human GBM specimens deriving from 162 patients, as well as 66 healthy control tissue specimens deriving from 27 patients, and analyzed the amount of 5-hydroxymethylcytosine (5hmC) in GBMs compared to normal brain and tumor infiltration zones. "
11/01/2015 - "The level of 5-hydroxymethylcytosine (5-hmC) converted by ten-eleven translocation (TET) family is decreased in cancers. "
|2.||Stomach Neoplasms (Stomach Cancer)
03/01/2014 - "A decrease in ten-eleven translocation 1 (TET1) transcript and 5-Hydroxymethylcytosine (5hmC) levels has recently been demonstrated in primary gastric cancer (GC). "
09/01/2013 - "Decreased 5-hydroxymethylcytosine (5-hmC) is an independent poor prognostic factor in gastric cancer patients."
07/01/2015 - "The rediscovery of 5-hydroxymethylcytosine, the ten-eleven translocation (TET) family, thymine-DNA glycosylase (TDG) and isocitrate dehydrogenase (IDH) have opened new avenues in the study of DNA demethylation pathways in gastric cancer (GC). "
|3.||Autistic Disorder (Autism)
12/15/2015 - "Genome-wide disruption of 5-hydroxymethylcytosine in a mouse model of autism."
01/01/2014 - "Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum."
01/01/2014 - "In this study we demonstrate that DNA isolated from the cerebellum of BTBR T+tf/J mice, a relevant mouse model of autism, and from human post-mortem cerebellum of individuals with autism, are both characterized by an increased levels of 8-oxo-7-hydrodeoxyguanosine (8-oxodG), 5-methylcytosine (5mC), and 5-hydroxymethylcytosine (5hmC). "
|4.||Prostatic Neoplasms (Prostate Cancer)
01/01/2015 - "High levels of 5-hydroxymethylcytosine (5hmC) is an adverse predictor of biochemical recurrence after prostatectomy in ERG-negative prostate cancer."
01/01/2015 - "The recent studies demonstrated that the global 5-hydroxymethylcytosine (5 hmC) level decreased in prostate cancer (PCa) involved the 5-methylcytosine (5 mC) hydroxymethylase, Ten-eleven translocation (TET)1 reduction. "
|5.||Alzheimer Disease (Alzheimer's Disease)
|1.||5-Methylcytosine (5 Methylcytosine)
|2.||DNA (Deoxyribonucleic Acid)
|3.||Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))
|4.||Thymine DNA Glycosylase
|6.||Proteins (Proteins, Gene)
|9.||A-Form DNA (A-DNA)
|1.||Prostatectomy (Retropubic Prostatectomy)