|1.||El-Kayat, Bara: 1 article (03/2012)|
|2.||Chin, Kuen Yeow: 1 article (03/2012)|
|3.||Hart, Andrew: 1 article (03/2012)|
|4.||Milne, Alistair: 1 article (03/2012)|
01/01/1982 - "Rheumatoid arthritis patients showed significant improvement in most measurements with both drugs, but overall results favored benoxaprofen, particularly in erythrocyte sedimentation rate and physician's global assessment. "
01/01/1982 - "Our study of 39 patients with rheumatoid arthritis suggests a trend for benoxaprofen therapy given over a prolonged period to retard the rheumatologic process when measured radiologically by both osseous defect and joint space narrowing rates. "
01/01/1980 - "Dose-range studies of benoxaprofen compared with placebo in patients with active rheumatoid arthritis."
11/01/1978 - "A double-blind cross-over trial showed that benoxaprofen was effective and well tolerated in rheumatoid arthritis. "
01/01/1982 - "Radiologic assessment of benoxaprofen therapy in rheumatoid arthritis."
01/01/1982 - "Benoxaprofen plasma profiles were obtained in 10 elderly patients (mean age 77 years) suffering from osteoarthritis and various underlying diseases. "
01/01/1982 - "A multicentre comparative crossover study of benoxaprofen in the treatment of osteoarthritis was undertaken by general practitioners in the United Kingdom. "
01/01/1980 - "Long-term treatment of symptomatic osteoarthritis with benoxaprofen. "
01/01/1982 - "Significant clinical improvement was apparent after one week of benoxaprofen therapy in rheumatoid arthritis and osteoarthritis. "
11/01/1982 - "Benoxaprofen undergoes hepatic metabolism via glucuronidation as the primary route of elimination and has a half-life of 28-35 hr. Clinical trials have demonstrated that its analgesic and anti-inflammatory properties are useful in the management of the signs and symptoms of rheumatoid arthritis and osteoarthritis. "
06/11/1983 - "The results showed that benoxaprofen improved clinical parameters of disease activity, including morning stiffness, walking time, tenderness and swelling of joints and pain rating, in 7 of the 10 patients studied. "
01/01/1980 - "Assessments of pain, function, and analgesic consumption showed that benoxaprofen had analgesic activity at all dose levels. "
01/01/1980 - "Statistically significant differences in favor of benoxaprofen were found for knee flexion and pain relief. "
02/01/1987 - "Most were taking benoxaprofen for osteoarthritis (53%) or non-specific musculoskeletal pain (39.9%). "
06/01/1977 - "Benoxaprofen has analgesic activity in tests where pain is accompanied by inflammation but not in other experimental models of pain. "
|4.||Psoriasis (Pustulosis Palmaris et Plantaris)
07/01/1983 - "Twenty-four patients with psoriasis completed a double-blind trial of benoxaprofen for their cutaneous lesions. "
01/01/1985 - "These results are compatible with the idea that benoxaprofen may improve psoriasis by interfering with monocyte function."
01/01/1985 - "To assess a potential pathogenic role of enhanced monocyte function in psoriasis, we determined monocyte chemotaxis and monocyte antibody-dependent cell-mediated cytotoxicity (ADCC) at week 0, 2, 4 and 8 in psoriatics being treated with benoxaprofen. "
01/01/1985 - "Enhanced monocyte activity is present in psoriasis, and benoxaprofen is a drug that inhibits several aspects of monocyte function. "
01/01/1985 - "Normalization of monocyte chemotaxis precedes clinical resolution of psoriasis treated with benoxaprofen."
11/01/1982 - "Benoxaprofen (Opren) is a nonsteroidal anti-inflammatory agent used in the treatment of arthritis. "
07/01/1982 - "The effect of benoxaprofen was examined on adjuvant-induced arthritis in rats by radiographic assessment of bone damage. "
01/01/1982 - "The ability of benoxaprofen to suppress bone damage associated with adjuvant-induced arthritis in rats was studied radiographically over a 49-day period. "
11/01/1982 - "Benoxaprofen: a new arthritis medication that causes phototoxicity."
01/01/1980 - "Benoxaprofen was also moderately active in inhibiting developing adjuvant-induced arthritis; however, it exhibited a potent response in established adjuvant arthritis, and it was the only compound tested which showed marked inhibition of the directional movement of mononuclear cells. "
|5.||Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
|7.||Arachidonic Acid (Vitamin F)
|8.||5,8,11,14-Eicosatetraynoic Acid (5,8,11,14 Eicosatetraynoic Acid)
|9.||Nordihydroguaiaretic Acid (Masoprocol)
|10.||12,20- dihydroxy- 5,8,10,14- eicosatetraenoic acid
|2.||Renal Dialysis (Hemodialysis)