|1.||Zhang, Lihai: 1 article (09/2014)|
|2.||Liu, Daohong: 1 article (09/2014)|
|3.||Tang, Peifu: 1 article (09/2014)|
|4.||Lu, Honghui: 1 article (09/2014)|
|5.||Song, Feixiang: 1 article (09/2014)|
|6.||Soromou, Lanan-Wassy: 1 article (11/2013)|
|7.||Li, Rui-sheng: 1 article (11/2013)|
|8.||Deng, Yan-hong: 1 article (11/2013)|
|9.||Gao, Hua-yi: 1 article (11/2013)|
|10.||Feng, Hai-hua: 1 article (11/2013)|
03/15/1984 - "8-methoxypsoralen and angelicin, locally applied to the skin of the rabbit, photosensitized erythema under UV irradiation to an approximately equal extent. "
01/01/1986 - "A good correlation has also been found between the formation of cross-linkages in DNA and the induction of erythema on skin; monofunctional furocoumarins, like methyl-angelicin derivatives, are unable to induce erythema, although they have very strong antiproliferative properties."
07/01/1981 - "While, as already observed, angelicin and 4,5'-dimethylangelicin failed to induce erythema on guinea-pig skin, 4'-methylangelicin derivatives proved to be phototoxic; however in comparison with the cross-linking psoralen, much higher amounts of substance and radiation doses were required. "
09/01/1983 - "The minimal erythema dose (MED) in the UVB area was approximately 1/3 of that in persons of skin type II. The application of furocoumarins (psoralens) increased light tolerance by 1 MED at 300-310 nm. Action spectrum studies with furocoumarins from Heracleum laciniatum showed the following order of potency: bergapten, pimpinellin, angelicin and sphondin. "
|2.||Acute Lung Injury
11/01/2013 - "Angelicin regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways."
11/01/2013 - "The purpose of this study was to investigate the protective ability of angelicin against inflammation in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and LPS-induced in vivo acute lung injury model. "
07/01/1981 - "In short-term experiments such as the studies on macromolecular synthesis in Ehrlich ascites cells, in which the assay is performed that after irradiation, before DNA repair an intervene significantly, 4'-methylangelicin derivatives produced an inhibition of DNA and RNA synthesis 10 times higher than angelicin, the parent compound, and about 3.5 times higher than 4,5'-dimethylangelicin and psoralen, all assumed as reference compounds. "
06/01/1990 - "A dose of angelicin (215 micrograms) equimolar to the highest dose of TMA combined with 1 J/cm2 of UVA radiation produced tumors in 28% of the mice (P greater than 0.05). "
10/01/2012 - "Taken together, our data shows that angelicin is an effective apoptosis-inducing natural compound of human SH-SY5Y neuroblastoma cells which suggests that this compound may have a role in future therapies for human neuroblastoma cancer."
09/01/2014 - "Tumor volume inhibition rates were 67.86% and 66.96%, respectively, in the psoralen and isopsoralen high-dose groups, and tumor weight inhibition rates were 49.47% and 47.87%. "
09/01/2014 - "Tumor volume inhibition rates were 43.75% and 40.18%, respectively, in the psoralen and isopsoralen low-dose groups, and tumor weight inhibition rates were 38.83% and 37.77%. "
01/01/2011 - "Apoptosis of tumor cell significantly increased after treated with psoralen and isopsoralen. "
|3.||DNA (Deoxyribonucleic Acid)
|4.||RNA (Ribonucleic Acid)
|1.||Photochemotherapy (Photodynamic Therapy)