|1.||Sora, Ichiro: 2 articles (10/2012 - 10/2007)|
|2.||Hall, F Scott: 2 articles (10/2012 - 10/2007)|
|3.||Uhl, George R: 2 articles (10/2012 - 10/2007)|
|4.||Leung, Yuk-Man: 1 article (01/2013)|
|5.||Kuo, Chang-Shin: 1 article (01/2013)|
|6.||Bello, Nicholas T: 1 article (01/2013)|
|7.||Wang, Jhi-Joung: 1 article (01/2013)|
|8.||Walters, Amy L: 1 article (01/2013)|
|9.||Cunha, Priscila P: 1 article (01/2013)|
|10.||Chen, Yu-Wen: 1 article (01/2013)|
01/01/2013 - "In in vitro studies, the voltage-clamp method was employed to examine whether nisoxetine blocked Na(+) currents in mouse neuroblastoma N2A cells. "
06/15/2001 - "In this study we have examined the effects of a range of local anaesthetic agents on the uptake of [3H]norepinephrine ([3H]NE) (as a surrogate for guanethidine) and the binding of [3H]nisoxetine to the NE transporter in cultured SH-SY5Y human neuroblastoma cells. "
|2.||Body Weight (Weight, Body)
04/01/2007 - "Consequently, the acute effects of DA and NE reuptake inhibition on energy homeostasis were determined by measuring food intake and body weight in mice following peripheral (intraperitoneal (i.p.)) administration of either BUP, a selective DA (GBR12783), or a selective NE (nisoxetine (NIS)) reuptake inhibitor. "
01/01/2013 - "The present studies determined how high-fat feeding and body weight gain alter the sensitivity to the feeding suppression and neural activation to a selective norepinephrine reuptake inhibitor, nisoxetine. "
08/01/1997 - "5. The results of this study demonstrate that inhibition of 5-HT and noradrenaline reuptake by sibutramine, venlafaxine, duloxetine, or by a combination of fluoxetine and nisoxetine, markedly reduces food intake in freely-feeding rats and suggest that this may be a novel approach for the treatment of obesity."
|4.||Alzheimer Disease (Alzheimer's Disease)
12/17/1993 - "The present study determined whether [3H]nisoxetine binding to norepinephrine transporter sites would be altered uniformly throughout the locus coeruleus in Alzheimer's disease. "
12/17/1993 - "The loss of [3H]nisoxetine binding to norepinephrine transporter sites may be attributed to a loss of norepinephrine transporter sites located on terminals of noradrenergic neurons in the locus coeruleus in Alzheimer's disease."
10/01/1980 - "In addition, desipramine increased the duration of tonic flexion and nisoxetine decreased the total duration of seizure. "
01/15/1977 - "Nisoxetine prevents the 6-hydroxydopamine induced decrease in post-decapitation convulsions."
01/12/1998 - "Pretreatment with prazosin (1 microgram/side) significantly diminished the anticonvulsant effectiveness of methoxamine and nisoxetine while prazosin, by itself, had no effects on the seizure intensity. "
01/12/1998 - "Desipramine (2, 4, 8 micrograms/side), nisoxetine (2, 4, 8 micrograms/side), and idazoxan (0.25, 1, 4 micrograms/side) all decreased the seizure severity in a dose-dependent fashion. "
10/01/1980 - "Nisoxetine and desipramine (inhibitors of norepinephrine reuptake) each exerted a suppressant effect on spinal cord seizures by decreasing the duration of tonic extension. "
|2.||Norepinephrine Plasma Membrane Transport Proteins (Norepinephrine Transporter)
|3.||Serotonin (5 Hydroxytryptamine)