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proquazone
nonsteroid anti-inflammatory agent; structure
Also Known As:
1-isopropyl-4-phenyl-7-methyl-2-(1H)-quinazoline; Biarison; RU 43-715
Networked:
30
relevant articles (
7
outcomes,
8
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinazolines: 402
proquazone: 30
Related Diseases
1.
Pain (Aches)
01/01/1978 - "
In both treatment groups a good result was achieved in more than 70% of the cases, but proquazone seemed to be more effective in reducing swelling and pain of knee.
"
10/27/1978 - "
The effectiveness of Biarison was shown in reference to parameters of pain (number of painful joints and intensity of joint pain, pain on motion and at rest).
"
06/01/1983 - "
Proquazone and indomethacin relieved pain and other dysmenorrhoeic symptoms similarly in 33 women.
"
01/01/1986 - "
Comparative study of Biarison and Voltaren in acute lumbar pain and lumbo-ischialgia.
"
01/01/1978 - "
Proquazone did significantly better than naproxen in improving ESR and nocturnal pain.
"
2.
Rheumatoid Arthritis
06/01/1982 - "
[Determination of efficacy of proquazone in chronic rheumatoid arthritis].
"
05/01/1987 - "
Evidence from small groups of patients with rheumatoid arthritis treated for a year or more suggests that proquazone may inhibit or arrest progression of bone erosions.
"
10/27/1978 - "
The effectiveness of Biarison vs. placebo was compared in an inter-individual double-blind study on 30 hospitalized patients with possible, definitive and classical rheumatoid arthritis.
"
10/27/1978 - "
[Treatment of rheumatoid arthritis with biarison.
"
06/30/1978 - "
Biarison was tested in 24 patients mainly with classical rheumatoid arthritis for its efficacy and tolerance.
"
3.
Acute Pain
05/01/1987 - "
Preliminary studies have confirmed the efficacy of proquazone in acute inflammatory disorders, and shown that it provides useful analgesic relief in acute pain states such as dysmenorrhoea, headache and after minor surgery.
"
4.
Headache (Headaches)
05/01/1987 - "
Preliminary studies have confirmed the efficacy of proquazone in acute inflammatory disorders, and shown that it provides useful analgesic relief in acute pain states such as dysmenorrhoea, headache and after minor surgery.
"
5.
Osteoarthritis
01/01/1980 - "
A double-blind study was carried out in 36 patients with osteoarthritis to evaluate the effectiveness and tolerance of 600 mg proquazone per day compared with 900 mg proquazone per day over a period of 3 months.
"
11/10/1978 - "
[Experiences with a new antiphlogistic agent biarison in the treatment of knee- and hip-joint arthroses].
"
05/01/1987 - "
Thus, at present, proquazone would seem to be as effective as other NSAIDs used in the management of rheumatoid arthritis and osteoarthritis.
"
05/01/1987 - "
Similarly, proquazone 300 to 900 mg/day is as effective as aspirin, diclofenac, ibuprofen, indomethacin and naproxen in patients with osteoarthritis.
"
Related Drugs and Biologics
1.
Indomethacin (Indometacin)
2.
Naproxen (Naprosyn)
3.
Analgesics (Analgesic Drugs)
4.
Diclofenac (SR 38)
5.
Aspirin (Acetylsalicylic Acid)
6.
Anti-Inflammatory Agents (Anti-Inflammatories)
7.
Ibuprofen (Motrin)
8.
Non-Steroidal Anti-Inflammatory Agents (NSAIDs)
9.
tolfenamic acid
10.
Ketoprofen (Orudis)
Related Therapies and Procedures
1.
Minor Surgical Procedures (Minor Surgery)
2.
Drug Therapy (Chemotherapy)