|1.||Fisher, Paul B: 8 articles (01/2011 - 01/2002)|
|2.||Sarkar, Devanand: 5 articles (01/2011 - 10/2002)|
|3.||Fisher, P B: 5 articles (10/2001 - 03/2000)|
|4.||Lee, Sang Kook: 4 articles (01/2015 - 02/2010)|
|5.||Hong, Ji-Young: 4 articles (01/2015 - 02/2010)|
|6.||Park, Hyen Joo: 3 articles (01/2015 - 10/2011)|
|7.||Yazdanparast, Razieh: 3 articles (09/2008 - 11/2005)|
|8.||Lebedeva, Irina V: 3 articles (09/2006 - 01/2002)|
|9.||Jiang, H: 3 articles (10/2001 - 11/2000)|
|10.||Madireddi, M T: 3 articles (10/2001 - 03/2000)|
01/01/1989 - "A second tumor promoter, mezerein, also dramatically reduced P210 levels in K562 cells and elevated them in EM2 cells. "
07/01/1985 - "The second stage tumor promoter mezerein is as effective as TPA in stimulating CL. "
05/03/1989 - "This study evaluated the skin tumor-promoting activity of mezerein in SENCAR mice. "
09/26/2002 - "Stage-II tumor promotion was accomplished by applying mezerein, BPO, COOH or H(2)O(2) to these mice twice weekly for 40 weeks. "
11/01/1996 - "Our data suggest that modulation of RARs could contribute to the neoplastic phenotype in mouse skin carcinogenesis and may be involved in the differential promoting activity of mezerein and 12-O-tetradecanoylphorbol-13-acetate, particularly for selecting tumors at high risk for malignant conversion."
11/01/1996 - "RARalpha was slightly reduced in papillomas promoted with 12-O-tetradecanoylphorbol-13-acetate (low risk) and markedly decreased or absent in papillomas promoted by mezerein (high risk). "
05/01/1992 - "Complete promotion with 9.0 nmol mezerein induced a total of 53 papillomas in 28 mice within 40 weeks, while 1.5 nmol 12-O-tetradecanoylphorbol-13-acetate (TPA), using the same application regime, resulted in a total of 298 papillomas in 58 mice. "
10/01/1989 - "Moreover, the pattern and magnitude of papilloma induction, yielding a peak at 16-20 weeks followed by a decline by 30-32 weeks, resembled that for TPA; mezerein, in contrast, induced a gradual but steady increase in the number of papillomas which did not reach the OHM level by 32 weeks. "
03/01/1988 - "Surprisingly, pretreatment with the stage II promoter, mezerein (2 micrograms), either 2 or 5 weeks prior to initiation, also gave papilloma responses similar to that induced with the standard two-stage promotion protocol (4.7 and 6.4 papillomas per mouse, respectively). "
03/01/1988 - "The papilloma response in mice, receiving pretreatments with 2 micrograms of 12-O-tetradecanoylphorbol-13-acetate (TPA) either 3 days, 1, 2, 3 or 5 weeks before initiation, was similar to that seen when TPA was given after initiation during stage I of promotion followed by stage II of promotion with mezerein (4-5 papillomas per mouse in all groups). "
05/01/1992 - "Skin carcinomas and micronucleus induction in epidermal keratinocytes following 12-O-tetradecanoylphorbol-13-acetate and mezerein treatment."
05/01/1992 - "However, 7.6% of the papillomas in the mezerein group progressed to carcinomas, compared with 0.7% in the TPA group. "
10/01/1989 - "Mezerein is a good second-stage promoter of papillomas, an inefficient complete promoter of papillomas, and an effective promoter of carcinomas. "
05/03/1989 - "However, the presence of two to four times more papillomas in some mezerein-treated groups did not lead to greater numbers of carcinomas than in the groups with fewer papillomas. "
05/03/1989 - "Higher ratios of carcinomas to papillomas were observed in mice promoted with mezerein than in mice receiving TPA promotion or two-stage promotion (TPA-mezerein). "
04/01/1986 - "The human monocytic leukemia cell line, THP-1, acquires macrophage-like characteristics following exposure to mezerein. "
01/01/2006 - "Daphnane-type diterpene esters as powerful agents for the treatment of leukemia."
01/01/1991 - "Human monocytic leukemia THP-1 cells were well-differentiated from nonfunctional promonocytes into macrophage-like cells by the induction with a combination of mezerein, retinoic acid, and aMycoplasma fermentans extract. "
01/01/1991 - "Human monocytic leukemia THP-1 cells were well-differentiated from nonfunctional promonocytes into macrophage-like cells by the induction with a combination of mezerein, retinoic acid, and a Mycoplasma fermentans extract. "
04/01/1990 - "Secretion of interleukin-1 beta by a leukemia cell line in response to lipopolysaccharide and mezerein."
|3.||Guanosine Triphosphate (GTP)
|8.||Adenylate Cyclase (Adenylyl Cyclase)
|2.||Fat-Restricted Diet (Diet, Fat Restricted)