|1.||Nishida, Ryuichi: 1 article (01/2013)|
|2.||Kajiwara, Eiji: 1 article (01/2013)|
|3.||Yamamoto, Atsuki: 1 article (01/2013)|
|4.||Itoh, Tomokazu: 1 article (01/2013)|
|5.||Nasu, Reishi: 1 article (01/2013)|
|6.||Fernández-Pérez, María Piedad: 1 article (06/2012)|
|7.||Sáez-Ayala, Magalí: 1 article (06/2012)|
|8.||Sánchez-del-Campo, Luis: 1 article (06/2012)|
|9.||Cabezas-Herrera, Juan: 1 article (06/2012)|
|10.||Montenegro, María F: 1 article (06/2012)|
08/08/1991 - "Failure to interconvert tetrahydrofolate cofactors to dihydrofolate in mitochondria of L1210 leukemia cells treated with trimetrexate."
03/25/1991 - "Rate and extent of interconversion of tetrahydrofolate cofactors to dihydrofolate after cessation of dihydrofolate reductase activity in stationary versus log phase L1210 leukemia cells."
12/01/1964 - "ON THE SIMILARITY OF DIHYDROFOLATE REDUCTASES FROM AMETHOPTERIN-SENSITIVE AND AMETHOPTERIN-RESISTANT MOUSE LEUKEMIA (L1210) CELLS."
10/15/1989 - "Folate analogs that inhibit dihydrofolate reductase result in only partial interconversion of tetrahydrofolate cofactors to dihydrofolate with preservation of the major portion of reduced cellular folate cofactors in L1210 leukemia cells. "
03/25/1991 - "Previous studies from this laboratory established that the rapid but partial interconversion of tetrahydrofolate cofactors to dihydrofolate after exposure of L1210 leukemia cells to antifolates cannot be due to direct feedback inhibition of thymidylate synthase by dihydrofolate or any other endogenous folylpolyglutamates when dihydrofolate reductase activity is abolished by antifolates. "
|4.||Acquired Immunodeficiency Syndrome (AIDS)
|5.||Breast Neoplasms (Breast Cancer)
02/01/1990 - "Isolation and characterization of a novel dihydrofolate formylating enzyme from human MCF-7 breast cancer cells."
06/15/1990 - "Interaction of methotrexate polyglutamates and dihydrofolate during leucovorin rescue in a human breast cancer cell line (MCF-7)."
05/25/1990 - "We have studied the roles of 5,10-methylenetetrahydrofolate (5,10-methylene-H4PteGlu) depletion and dihydrofolate (H2PteGlu) accumulation in the inhibition of de novo thymidylate synthesis by methotrexate (MTX) in human MCF-7 breast cancer cells. "
10/05/1987 - "We have investigated the role of dihydrofolate (H2PteGlu) accumulation in the inhibition of de novo purine synthesis by methotrexate (MTX) in human MCF-7 breast cancer cells. "
08/01/1985 - "We report the enhanced inhibitory potency of methotrexate (MTX) polyglutamates and dihydrofolate pentaglutamate on the catalytic activity of phosphoribosylaminoimidazolecarboxamide (AICAR) transformylase purified from MCF-7 human breast cancer cells. "
|1.||Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)
|3.||5,6,7,8-tetrahydrofolic acid (tetrahydrofolate)
|6.||Folic Acid Antagonists
|10.||Folic Acid (Vitamin M)