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salicyl alcohol (saligenin)
RN given refers to parent cpd; saligenin is the aglycone of salicin; structure; it is oxidatively metabolized to gentisic acid
Also Known As:
saligenin
; 2-methylol phenol; 2-monomethylolphenol; o-hydroxybenzyl alcohol; salicyl alcohol, (ar)-isomer; salicyl alcohol, disodium salt; salicyl alcohol, monosodium salt
Networked:
6
relevant articles (
0
outcomes,
2
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzyl Compounds: 2
Benzyl Alcohols: 7
salicyl alcohol: 6
Alcohols: 595
Benzyl Alcohols: 7
salicyl alcohol: 6
Experts
1.
Aalto-Korte, Kristiina
: 1 article (02/2005)
2.
Henriks-Eckerman, Maj-Len
: 1 article (02/2005)
3.
Jolanki, Riitta
: 1 article (02/2005)
4.
Välimaa, Jarmo
: 1 article (02/2005)
Related Diseases
1.
Body Weight (Weight, Body)
01/01/1988 - "
In the present study, 4-wk-old White Leghorn chickens were administered a single dose of 500 mg tri-o-tolyl phosphate (TOTP)/kg body weight or 100 mg o-tolyl saligenin phosphate (TSP)/kg body weight via the oral, intramuscular, or intraperitoneal route.
"
01/01/1989 - "
A single intraperitoneal injection of beta NF at 80 mg/kg body weight 48 h prior to administration of o-tolyl saligenin phosphate (TSP), the neuroactive metabolite of tri-o-tolyl phosphate (TOTP), caused a significant increase in hepatic microsomal cytochrome P-450 concentrations and aniline hydroxylase activities after 72 h in both strains.
"
2.
Neuroblastoma
03/13/1998 - "
Therefore, this study examined concentration-related OP-induced inhibition of CbxE in human SH-SY5Y and mouse NB41A3 neuroblastoma cells with 11 active esterase inhibitors: paraoxon, malaoxon, chlorpyrifos-oxon, tolyl saligenin phosphate (TSP), phenyl saligenin phosphate (PSP), diisopropyl phosphorofluoridate (DFP), mipafox, dichlorvos, trichlorfon, dibutyryl dichlorovinyl phosphate (DBVP), and dioctyl dichlorovinyl phosphate (DOVP).
"
3.
Hypersensitivity (Allergy)
12/01/1997 - "
Contact allergy to salicyl alcohol in aspen bark.
"
02/01/2005 - "
Besides salicyl alcohol, salicylaldehyde is also recommended to be used to screen for contact allergy to aspen.
"
4.
Allergic Contact Dermatitis
02/01/2005 - "
There is 1 previous report of allergic contact dermatitis from salicyl alcohol in aspen bark.
"
02/01/2005 - "
Allergic contact dermatitis from salicyl alcohol and salicylaldehyde in aspen bark (Populus tremula).
"
5.
Hypocalcemia
11/01/1982 - "
Among of SA analogues, acetylsalicylic acid, salicylaldehyde, salicyl-alcohol, methyl salicylate and SA evoked a hypocalcemia in rats and mice but the other analogues had no effect by their single administration.
"
Related Drugs and Biologics
1.
Phosphates (Orthophosphate)
2.
tri-o-cresyl phosphate (TOCP)
3.
tris-O-tolyphosphine (TOTP)
4.
Trichlorfon (Metrifonate)
5.
Paraoxon (E600)
6.
Isoflurophate (DFP)
7.
Esterases
8.
Dichlorvos
9.
malaoxon
10.
phenylsaligenin cyclic phosphate (PSCP)
Related Therapies and Procedures
1.
Intraperitoneal Injections