|1.||Qian, Zhiyu: 10 articles (07/2012 - 10/2005)|
|2.||Sheng, Liang: 6 articles (09/2010 - 10/2005)|
|3.||Yang, Lina: 5 articles (07/2012 - 10/2008)|
|4.||Xi, Liang: 4 articles (07/2012 - 10/2005)|
|5.||Ji, Hui: 4 articles (01/2012 - 10/2008)|
|6.||Dhar, Animesh: 4 articles (01/2012 - 05/2003)|
|7.||Wen, Na: 4 articles (01/2007 - 10/2005)|
|8.||Carmona, Manuel: 3 articles (01/2015 - 01/2014)|
|9.||Mancini, Andrea: 3 articles (01/2015 - 01/2014)|
|10.||Umigai, Naofumi: 3 articles (03/2013 - 01/2011)|
01/01/2015 - "Crocetin supplementation in the MCA mice also showed protection against cervical cancer. "
01/01/2012 - "This review discusses the studies on cancer preventive potential of crocetin and its future use as an anticancer agent."
07/01/2006 - "Tumor incidence and histopathological studies proves crocetin is a potent antitumour agent."
01/01/2014 - "The aim of the present report was to investigate if SE, crocetin (CCT), and CR affected in vivo tumor growth of two aggressive PCa cell lines (PC3 and 22rv1) which were xenografted in male nude mice treated by oral gavage with SE, CR, and CCT. "
01/01/2012 - "Crocetin affects the growth of cancer cells by inhibiting nucleic acid synthesis, enhancing anti-oxidative system, inducing apoptosis and hindering growth factor signaling pathways. "
10/15/2014 - "Protective effects of crocetin pretreatment on myocardial injury in an ischemia/reperfusion rat model."
10/15/2014 - "This study aims to investigate whether crocetin repairs myocardial damage in vivo after ischemia reperfusion (I/R) and the mechanisms underlying its cardioprotective effects. "
11/01/2013 - "According to our data, crocetin (8 mg/kg) could properly protect cerebrocortical and hippocampus neurons against ischemia. "
03/05/2013 - "The histological analysis revealed that ischemia/reperfusion (I/R) decreased the cell number in the ganglion cell layer (GCL) and the thickness of inner nuclear layer (INL), and that crocetin inhibited GCL and INL. "
03/05/2013 - "These findings indicate that crocetin prevented ischemia-induced retinal damage through its inhibition of oxidative stress."
01/01/2011 - "Crocetin reduces activation of hepatic apoptotic pathways and improves survival in experimental hemorrhagic shock."
01/01/2010 - "Effect of crocetin on blood pressure restoration and synthesis of inflammatory mediators in heart after hemorrhagic shock in anesthetized rats."
10/01/2005 - "Molecular basis of protective effect by crocetin on survival and liver tissue damage following hemorrhagic shock."
09/01/1993 - "The effect of crocetin on hemorrhagic shock in rats."
07/01/2012 - "The main objective of the study was to evaluate whether crocetin, a natural product from Gardenia jasminoides Ellis, has beneficial effects on renal dysfunction caused by hemorrhagic shock and resuscitation in rats. "
|4.||Cardiomegaly (Heart Hypertrophy)
04/01/2006 - "Crocetin markedly reduced the content of lipid peroxidation (LPO), increased the GSH-Px and SOD activity in cardiac hypertrophy, and significantly improved the myocardial pathological histological changes induced by NE. "
03/01/2004 - "To study the influence of crocetin on cardiac hypertrophy induced by overloading pressure in rats. "
05/01/2009 - "The results showed that crocetin (1-10 microM) dose-dependently blocked cardiac hypertrophy induced by angiogensin II (Ang II; 1 microM) in vitro. "
05/01/2009 - "Because crocetin represses oxidative stress in vitro and in vivo, we have suggested that crocetin would repress cardiac hypertrophy by targeting oxidative stress-dependent signalling. "
05/01/2009 - "Crocetin protects against cardiac hypertrophy by blocking MEK-ERK1/2 signalling pathway."
01/01/2011 - "This study demonstrated that administration of crocetin to experimental animals during resuscitation from shock significantly improved postshock survival and reduced apoptosis. "
01/01/2011 - "Control animals were sham-treated with surgical preparation, without shock or resuscitation, and with and without crocetin. "
07/01/2006 - "Crocetin modified the hepatic mRNA expression of cytokines and iNOS in a shock model. "
07/01/2006 - "The group resuscitated from shock with crocetin had mRNA expression for TNF-alpha, IL-1beta, and iNOS in fewer animals than either of the other shock groups and was no different from the sham control group. "
07/01/2012 - "These results suggested that crocetin blocks inflammatory cascades by inhibiting production of reactive oxygen species and restoring superoxide dismutase activity to ameliorate renal dysfunction caused by hemorrhage shock and resuscitation."
|1.||Adenosine Triphosphate (ATP)
|2.||Tretinoin (Retinoic Acid)
|4.||Sodium Selenite (Selenite)
|10.||Oxidopamine (6 Hydroxydopamine)
|2.||Traditional Medicine (Folk Remedies)
|5.||Heterologous Transplantation (Xenotransplantation)