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thiodiacetic acid

vinyl chloride metabolite in urine of rats

Also Known As:

thiodiglycolic acid; 2,2'-thiobisacetic acid

Networked: 8 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Thioglycolates: 2
        thiodiacetic acid: 8
- Sulfur Compounds: 278
  - Sulfhydryl Compounds: 4168
    - Thioglycolates: 2
      - thiodiacetic acid: 8

Experts

1.	Chiang, Hung-Che: 2 articles (10/2019 - 01/2019)
2.	Chuang, Hung-Yi: 2 articles (10/2019 - 01/2019)
3.	Huang, Po-Chin: 2 articles (10/2019 - 01/2019)
4.	Liao, Kai-Wei: 2 articles (10/2019 - 01/2019)
5.	Wang, Chih-Wen: 2 articles (10/2019 - 01/2019)
6.	Yu, Ming-Lung: 2 articles (10/2019 - 01/2019)
7.	Funakoshi, Atsuko: 1 article (01/2022)
8.	Honda, Tetsuya: 1 article (01/2022)
9.	Kurihara, Kazuo: 1 article (01/2022)
10.	Morimoto, Hiroki: 1 article (01/2022)

Related Diseases

1.	Mitochondrial Diseases (Mitochondrial Disease) 05/01/2004 - "CEM is metabolized to thiodiglycolic acid, a chemical that causes mitochondrial dysfunction. " 03/01/1998 - "Additionally, thiodiglycolic acid (30 microM) inhibited oxidation of palmitic acid but not palmitoyl-L-carnitine in isolated rat liver mitochondria, indicating that it either sequesters carnitine or inhibits carnitine palmitoyltransferase I. This study elucidates a specific mitochondrial dysfunction induced by thiodiglycolic acid which may contribute to the adverse effects associated with ifosfamide chemotherapy."
2.	Body Weight (Weight, Body) 01/01/1985 - "The studies were focussed on: body weight, liver weight, activity of enzymes in the blood serum, activity of glutathione S-transferase in the liver cytoplasmatic and microsomal fraction, content of free non-protein sulfhydryl groups (NPSH) in the liver and urinary excretion of thiodiglycolic acid (TDGA). "
3.	Drug Eruptions (Drug Eruption) 07/01/2005 - "Thiodiglycolic acid as a possible causative agent of fixed drug eruption provoked only after continuous administration of S-carboxymethyl-L-cysteine: case report and review of reported cases." 01/01/2022 - "Multiple fixed drug eruption due to carbocysteine: Presence of circulating interferon-γ-producing CD8+ T cells reactive with its night metabolite thiodiglycolic acid."
4.	Non-alcoholic Fatty Liver Disease 10/01/2019 - "Urinary thiodiglycolic acid is associated with increased risk of non-alcoholic fatty liver disease in children living near a petrochemical complex."
5.	Fibrosis (Cirrhosis) 01/01/2019 - "We aimed to assess the association among urinary thiodiglycolic acid (TDGA) level, abnormal liver function, and hepatic fibrosis in school-aged children living near a petrochemical complex. " 01/01/2019 - "Association between urinary thiodiglycolic acid level and hepatic function or fibrosis index in school-aged children living near a petrochemical complex."

Related Drugs and Biologics

1.	Palmitic Acid (Hexadecanoic Acid)
2.	Proteins (Proteins, Gene)
3.	Ifosfamide
4.	Glutathione Transferase (Glutathione S-Transferase)
5.	Enzymes
6.	Carnitine O-Palmitoyltransferase (Carnitine Palmitoyltransferase II)
7.	Carnitine (L-Carnitine)
8.	Carbocysteine (S-Carboxymethylcysteine)
9.	Interferons

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)