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tiamenidine
Also Known As:
2-chloro-4-methyl-3-(2'-imidazolin-2'-ylamino)thiophene; HOE 440; thiamenidine; tiamenidine monohydrochloride
Networked:
4
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiophenes: 257
tiamenidine: 4
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Thiophenes: 257
tiamenidine: 4
Related Diseases
1.
Essential Hypertension
11/01/1984 - "
Withdrawal phenomena in subjects with essential hypertension on clonidine or tiamenidine.
"
11/01/1980 - "
Ten patients, four male, six female, aged 28--64 years, with essential hypertension, were treated for one year with an imidazoline derivative, tiamenidine.
"
10/01/1979 - "
Tiamenidine, a centrally acting antihypertensive drug in essential hypertension [proceedings].
"
11/01/1980 - "
Changes in blood pressure, heart rate, and sympathetic activity on abrupt withdrawal of tiamenidine (HOE 440) in essential hypertension.
"
2.
Tachycardia (Tachyarrhythmias)
04/01/1980 - "
Significant tachycardia was demonstrated in all cats 15-19 h after cessation of treatment with tiamenidine with no evidence of blood pressure elevation; the tachycardia was absent 48 h after the final dose.
"
3.
Bradycardia
04/01/1980 - "
In conscious renal hypertensive cats prepared with permanent indwelling arterial catheters oral administration of clonidine (0.05 mg x 3 daily) clonidine (0.0125 mg x 3 daily), or tiamenidine (0.25 mg x 3 daily) induced hypotension and bradycardia during 6 days of treatment, although these responses were not well sustained.
"
Related Drugs and Biologics
1.
Clonidine (ST 155)
2.
tiamenidine
3.
Imidazolines
4.
Antihypertensive Agents (Antihypertensives)
Related Therapies and Procedures
1.
Catheters
2.
Withholding Treatment
3.
Controlled Hypotension
4.
Oral Administration