|1.||Smith, Tracy K: 3 articles (05/2005 - 03/2003)|
|2.||Johnson, Ian T: 3 articles (05/2005 - 03/2003)|
|3.||Lund, Elizabeth K: 2 articles (05/2005 - 08/2004)|
|4.||Clarke, Rosemary G: 2 articles (05/2005 - 08/2004)|
|5.||de Haro-Bailon, Antonio: 1 article (01/2015)|
|6.||Muñoz-Serrano, Andrés: 1 article (01/2015)|
|7.||Lozano-Baena, María-Dolores: 1 article (01/2015)|
|8.||Obregón-Cano, Sara: 1 article (01/2015)|
|9.||Tasset, Inmaculada: 1 article (01/2015)|
|10.||Alonso-Moraga, Ángeles: 1 article (01/2015)|
01/01/2014 - "Sinigrin was found to significantly inhibit the proliferation of liver tumor cells; the number of surface tumors in the rat liver was dramatically reduced. "
01/01/2015 - "Antigenotoxicity and Tumor Growing Inhibition by Leafy Brassica carinata and Sinigrin."
01/01/2004 - "Sinigrin showed no proliferating effect on the tumor cells tested. "
10/01/1988 - "However, dietary sinigrin plus NNK resulted in a significant incidence of pancreatic tumors, a rare occurrence in F344 rats. "
10/01/1988 - "These results suggested that dietary sinigrin might reduce the incidence of NNK-induced hepatic tumors with no effect on NNK tumorigenesis of the lung and nasal cavity, whereas I3C might increase hepatic tumor incidence and reduce NNK tumorigenesis of the lung and nasal cavity. "
|2.||Aberrant Crypt Foci
02/01/1998 - "Inhibition of dimethylhydrazine-induced aberrant crypt foci and induction of apoptosis in rat colon following oral administration of the glucosinolate sinigrin."
02/01/1998 - "In a second experiment, rats were given sinigrin (400 microg/g diet) 22 h after the second of two injections of DMH; the level of apoptosis was measured after 48 h and the numbers of aberrant crypt foci (ACF) were measured after 42 days. "
03/01/2003 - "We have shown previously that oral administration of the isolated glucosinolate sinigrin induces apoptosis, and suppresses aberrant crypt foci in the colonic mucosa of rats treated previously with 1,2-dimethylhydrazine (DMH). "
|3.||Colorectal Neoplasms (Colorectal Cancer)
05/18/2005 - "We used raw juice extracted from Brussels sprouts rich in the glucosinolate sinigrin to explore the effect of naturally occurring glucosinolate breakdown products on cell cycle progression and apoptosis in human colorectal carcinoma cells (HT29). "
08/01/2004 - "We have examined the effects of allyl-isothiocyanate (AITC), a major breakdown product of the glucosinolate sinigrin, on proliferation and death of colorectal cancer cells. "
|5.||Liver Neoplasms (Liver Cancer)
01/01/2014 - "The results suggest that sinigrin exerts important anti-proliferative activities in carcinogen-induced hepatocarcinogenesis in rats, and highlight the potential of sinigrin as an anti-cancer agent for liver cancer. "
01/01/2014 - "Sinigrin induced apoptosis of liver cancer cells through up-regulation of p53 and down-regulation of Bcl-2 family members and caspases. "
|2.||Cyclooxygenase 2 (Cyclooxygenase-2)
|5.||Merozoite Surface Protein 1 (MSA1)
|6.||1,2-Dimethylhydrazine (1,2 Dimethylhydrazine)