|1.||Souza, Adelson A: 1 article (07/2014)|
|2.||De Souza, Nataly Araujo: 1 article (07/2014)|
|3.||Silva, Vanderlei Campos: 1 article (07/2014)|
|4.||Rangel, Elizabeth Ferreira: 1 article (07/2014)|
|5.||De Andrade-Coelho, Cláudia Alves: 1 article (07/2014)|
|6.||Gonzalez, Marcelo Salabert: 1 article (07/2014)|
|7.||Soares, Darly G: 1 article (06/2014)|
|8.||Godin, Adriana M: 1 article (06/2014)|
|9.||Machado, Renes R: 1 article (06/2014)|
|10.||Coelho, Márcio M: 1 article (06/2014)|
01/01/1992 - "Given through a blood meal, azadirachtin affected the immune reactivity as shown by a significant reduction in numbers of hemocytes and consequently nodule formation following challenge with Enterobacter cloacae beta 12, reduction in ability to produce antibacterial activities in the hemolymph when injected with bacteria, and decreased ability to destroy the infection caused by inoculation of E. "
09/01/1992 - "Studies were carried out on the effects of azadirachtin on the course of Trypanosoma cruzi infection in the gut of different triatomine vector species. "
03/01/1999 - "triatomae infection (12 weeks p.i.), feeding of azadirachtin did not affect the population density and composition. "
03/01/1999 - "Treatment with azadirachtin (1 microg ml(-1)) via a blood meal and a concurrent infection with B. "
03/01/1999 - "In established infections of controls without azadirachtin treatment, the small intestine of fifth-instar T. "
06/01/2010 - "The present study was designed to investigate the cellular and molecular mechanisms by which azadirachtin and nimbolide exert cytotoxic effects in the human cervical cancer (HeLa) cell line. "
02/11/2011 - "Overall, our data suggest that azadirachtin interacts with retinoic acid receptors and suppresses ATRA binding, inhibits falling off the receptors, and activates transcription factors like CREB, Sp1, NF-κB, etc. Thus, azadirachtin exerts anti-inflammatory and anti-metastatic responses by a novel pathway that would be beneficial for further anti-inflammatory and anti-cancer therapies."
06/01/2010 - "Antioxidants such as azadirachtin and nimbolide that can simultaneously arrest the cell cycle and target multiple molecules involved in mitochondrial apoptosis offer immense potential as anti-cancer therapeutic drugs."
06/01/2010 - "The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells."
04/25/2011 - "Thirty-five limonoids, including 15 of the azadiradione type (1-15), five of the gedunin type (16-20), four of the azadirachtin type (21-24), nine of the nimbin type (25-33), and two degraded limonoids (34, 35), isolated from Azadirachta indica seed extracts, were evaluated for their cytotoxic activities against five human cancer cell lines. "
06/01/2014 - "In conclusion, this study demonstrates the activity of azadirachtin in experimental models of nociceptive and inflammatory pain, and also in models of acute and chronic inflammation. "
06/01/2014 - "In the present study, we investigated the effects induced by azadirachtin in experimental models of pain and inflammation in mice. "
06/01/2014 - "Finally, multiple mechanisms, including the inhibition of the production of inflammatory mediators and activation of endogenous opioid pathways, may mediate azadirachtin activities in experimental models of inflammation and pain."
06/01/2014 - "Azadirachtin (120 mg/kg) also inhibited the nociceptive response in models of nociceptive (hot plate) and inflammatory (writhing induced by zymosan) pain. "
06/01/2014 - "The activity of azadirachtin (120 mg/kg) in the model of nociceptive pain was attenuated by a nonselective opioid antagonist, naltrexone (10 mg/kg, i. p.), but not by a nonselective serotonergic antagonist, cyproheptadine. "
|1.||Retinoic Acid Receptors (Retinoic Acid Receptor)
|2.||Transcription Factors (Transcription Factor)
|6.||Cadmium Chloride (Cadmium Dichloride)
|10.||Petroleum (Crude Oil)
|1.||Transplantation (Transplant Recipients)