palytoxin

01/19/2016 - "In this study, we demonstrate the presence of high levels of palytoxins (palytoxin and hydroxypalytoxin) in both soft coral and seawater from a home marine aquarium involved in the poisoning of a whole family. "
01/01/2013 - "In our present study, an LC-MS/MS method for palytoxin and its analogues in the blue humphead parrotfish samples causing the human poisoning cases in 2011 was developed and the samples were analysed by using the newly developed LC-MS/MS method. "
12/20/2021 - "This is a case report of three family members admitted to a hospital with symptoms compatible with palytoxin poisoning after cleaning an aquarium. "
10/03/2020 - "There is no specific treatment for PSP or palytoxin poisoning."
10/03/2020 - "Palytoxin poisoning occurred in a dog after it chewed coral removed from an aquarium. "

11/01/2007 - "Palytoxin, found in marine fish, has been associated with rhabdomyolysis, and may serve as a model for further study of the suspected toxin responsible for rhabdomyolysis after consumption of fresh water fish. "
03/01/1998 - "A 55-year-old man had rhabdomyolysis and myocardial damage induced by palytoxin. "
03/01/1998 - "Rhabdomyolysis and myocardial damage induced by palytoxin, a toxin of blue humphead parrotfish."
01/01/2022 - "From late 2016 to early 2021, cases of Haff disease, a rare cause of rhabdomyolysis, possibly due to poisoning by palytoxin-like compounds in seafood, were detected in Salvador, Brazil. "

09/01/2008 - "In the study of the marine toxin palytoxin (PTX), FETAX has revealed evident impacts on embryo mortality, teratogenesis and growth at the two highest (370 and 37nM) concentrations used. "

12/01/1988 - "Unlike the results of previous studies with another tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, palytoxin did not induce squamous differentiation of normal bronchial epithelial cells and was equally cytotoxic for normal human bronchial epithelial cells, a human lung tumor cell line, and human bronchial epithelial cells immortalized by infection with adenovirus 12-SV40 hybrid virus (BEAS-2B cells). "

01/01/2012 - "A comparison between haemolysis neutralization assay and HR LC-MS results showed a good correlation between haemolytic effect and total toxin content measured through HR LC-MS. Considering the increasing need for rapid and sensitive methods to detect palytoxin in natural samples, the haemolytic assay appears a useful method for preliminary quantification of the whole of palytoxin-like compounds in algal extracts."
10/01/2010 - "injection, and an extract of Ostreopsis sp. was negative in the palytoxin haemolysis neutralisation assay."
02/01/2009 - "A comparative study testing toxic mussel extracts by LC (liquid chromatography)-MS/MS (tandem MS), MBA (mouse bioassay), haemolysis neutralization assay and a cytotoxicity test indicated that our method is suitable for the routine determination and monitoring of palytoxins and palytoxin-like compounds."
11/01/2001 - "From these results, it was concluded that sheep erythrocyte hemolysis was caused by palytoxin or palytoxin-like factors present in the fish extracts. "
01/01/1999 - "The causative toxin was identified as palytoxin or its analogs based on its cytotoxicity, delayed hemolysis, neutralization with an anti-palytoxin antibody, chromatographic properties on different columns, and MS data. "