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flutonidine (ST 600)

RN given refers to parent cpd
Also Known As:
ST 600; 2-(5-fluoro-o-toluidine)-2-imidazoline; flutonidin; flutonidine monohydrochloride; 5-fluoro-2-methylimidazolidinylidenebenzamine
Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Marchal, F: 1 article (01/2011)
2. Chenuel, B: 1 article (01/2011)
3. Demoulin, B: 1 article (01/2011)
4. Poussel, M: 1 article (01/2011)
5. Varechova, S: 1 article (01/2011)

Related Diseases

1. Hypertension (High Blood Pressure)
05/19/1983 - "30 patients (9 man and 21 women, mean age 60.5), affected by mild-moderate essential hypertension, have been randomized in two homogeneous groups of 15 patients, and treated respectively with flutonidin (F) 2 mg/day and clonidine (C) 0.3 mg/day for a period of 15 days at the Hospital. "
01/01/1977 - "5-Fluoro-2-methyl-imidazolidinylidene-benzamine-hydrochloride (flutonidin, ST 600), a new antihypertensive imidazoline compound, was tested over 3 weeks in 20 patients with moderate to severe hypertension. "
12/01/1976 - "1. The cardio-renal haemodynamic and endocrine effects of the anti-hypertensive agents 2-(2,6-dichlorophenylamine)-2-imidazoline hydrochloride (clonidine, St 155) and 2-(5-fluor-o-toluidine)-2-imidazoline hydrochloride (St 600) were investigated in twelve patients with essential hypertension. "
09/01/1975 - "The effects of the antihypertensive imidazoline compounds 2-(5 fluor-0-toluidine)-2-imidazoline hydrochloride (ST 600) and 2-(2, 6 dichlorophenylamine)-2-imidazoline hydrochloride (ST 155, clonidine, Catapres) on intra-arterial pressure, cardiac output, stroke volume, heart rate, total peripheral resistance, renal blood flow, glomerular filtration rate, renal vascular resistance, plasma volume, plasma renin and aldosterone concentration were studied in five patients with essential hypertension. "
04/01/1975 - "The effects of the antihypertensive imidazoline compounds 2-(5 fluor-0-toluidine)-2-imidazoline hydrochloride (ST 600) and 2-(2, 6 dichlorophenylamine)-2-imidazoline hydrochloride (ST 155, catapres) on intra-arterial pressure, cardiac output, stroke volume, heart rate, total peripheral resistance, renal blood flow, glomerular filtration rate, renal vascular resistance, plasma volume, plasma renin and aldosterone concentration were studied in five patients with essential hypertension. "
2. Tachycardia (Tachyarrhythmias)
3. Premature Cardiac Complexes (Extrasystoles)
4. Cough

Related Drugs and Biologics

1. Clonidine (ST 155)
2. Renin
3. Aldosterone
4. flutonidine (ST 600)
5. Ouabain (G Strophanthin)
6. Antihypertensive Agents (Antihypertensives)