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N-methyladenosine

is a inhibitor of cell differentiation

Also Known As:

6-methyladenosine; N(6)-methyladenosine; N(6)mAdo; N6-methyladenosine; N6-methyladenosine (m6A)

Networked: 1723 relevant articles (5 outcomes, 138 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        N-methyladenosine: 1723
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - N-methyladenosine: 1723
  - Ribonucleosides: 49
    - Adenosine: 12431
      - N-methyladenosine: 1723

Experts

1.	He, Chuan: 17 articles (01/2022 - 10/2011)
2.	Chen, Jianjun: 13 articles (01/2021 - 01/2017)
3.	Liu, Jun: 11 articles (07/2022 - 01/2018)
4.	Liu, Wei: 10 articles (07/2022 - 04/2019)
5.	He, Jing: 10 articles (01/2022 - 01/2020)
6.	Su, Rui: 10 articles (01/2022 - 01/2017)
7.	Wang, Wei: 9 articles (12/2022 - 01/2018)
8.	Zhao, Wei: 9 articles (09/2022 - 11/2019)
9.	Liu, Xin: 9 articles (05/2022 - 01/2019)
10.	Li, Li: 9 articles (01/2022 - 01/2017)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2023 - "The physiological functions of N6-methyladenosine methylation in cancer have been the focus of studies in recent years. " 01/01/2023 - "Studies show strong links between N6-methyladenosine (m6A) modification and metabolic recombination of cancer cells. " 09/23/2022 - "Studies have demonstrated that N6-methyladenosine (m6A) can affect the invasion of immune cells in TME as well as cancer development. " 08/01/2022 - "Most previous studies have focused on the intrinsic carcinogenic pathways of tumors; however, little is known about the potential role of N6-methyladenosine (m6A) methylation in the tumor immune microenvironment (TIME). " 05/23/2022 - "Several studies have revealed that N6-methyladenosine (m6A) regulation is involved in various biological processes and cancer progression. "
2.	Inflammation (Inflammations) 03/01/2023 - "Aβ induces inflammatory responses in RPE cells and recent studies demonstrate the N6-methyladenosine (m6A) regulatory role in RPE cell inflammation. " 01/01/2022 - "Recent studies have demonstrated the epigenetic regulation of N6-methyladenosine (m6A) in the development of inflammation. " 01/01/2024 - "It is reported that N6-methyladenosine (m6A) RNA methylation regulates the polarization of macrophages and affects the development of inflammation. " 11/01/2023 - "N6-methyladenosine methylation regulator RBM15 promotes the progression of diabetic nephropathy by regulating cell proliferation, inflammation, oxidative stress, and pyroptosis through activating the AGE-RAGE pathway." 01/01/2023 - "Microglia-mediated inflammation is a major contributor to the brain damage in cerebral ischemia and reperfusion (I/R) injury, and N6-Methyladenosine (m6A) has been implicated in cerebral I/R injury. "
3.	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 09/27/2023 - "This study aims to clarify the N6-methyladenosine (m6A) modification of LINC01006, which is involved in migration, invasion and proliferation of non-small cell lung cancer (NSCLC). " 01/01/2022 - "This study aimed to investigate the effects of N6-methyladenosine (m6A) methylation of circ_SFMBT2 (circ_0017628) on non-small-cell lung cancer (NSCLC) and its underlying mechanisms. " 12/01/2023 - "The N6-methyladenosine (m6A) and long noncoding RNAs (lncRNAs) have been widely reported to participate in the development of non-small cell lung cancer. " 01/01/2022 - "Distinguishing between N6-methyladenosine (m6A)-associated long noncoding RNAs (lncRNAs) is crucial in non-small-cell lung cancer (NSCLC) patients. " 01/01/2021 - "Aberrant N6-methyladenosine (m6A) RNA methylation regulatory genes and related gene alternative splicing (AS) could be used to predict the prognosis of non-small cell lung carcinoma. "
4.	Heart Failure 01/01/2022 - "Exercise training ameliorates myocardial phenotypes in heart failure with preserved ejection fraction by changing N6-methyladenosine modification in mice model." 03/21/2023 - "We explored N6-methyladenosine (m6A) RNA methylation as one of the gene regulatory mechanisms in heart failure (HF) biology. " 12/01/2022 - "N6-methyladenosine (m6A) RNA modification in the pathophysiology of heart failure: a narrative review." 01/01/2022 - "N6-methyladenosine (m6A) methylation modification was involved in various cardiovascular diseases such as coronary heart disease and heart failure, although its influence on HCM remains unclear. " 01/01/2022 - "N6-methyladenosine (m6A) plays important roles in various cardiovascular diseases (CVDs), including cardiac hypertrophy and heart failure. "
5.	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 08/08/2023 - "To explore the N6-methyladenosine (m6A) methylation abnormality of mRNAs and its potential roles in the mouse model of polycystic ovary syndrome (PCOS). " 08/08/2023 - "Alteration of the N6-methyladenosine methylation landscape in a mouse model of polycystic ovary syndrome." 04/12/2023 - "N6-methyladenosine regulator-mediated methylation modification patterns and immune infiltration characterization in Polycystic Ovary Syndrome (PCOS)." 01/01/2023 - "Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome."

Related Drugs and Biologics

1.	6-methyladenine
2.	Messenger RNA (mRNA)
3.	Proteins (Proteins, Gene)
4.	Biomarkers (Surrogate Marker)
5.	Immune Checkpoint Inhibitors
6.	Butyric Acid (Butanoic Acid)
7.	Volatile Fatty Acids
8.	P-2 (P 2)
9.	RNA (Ribonucleic Acid)
10.	Methyltransferases

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Immunotherapy
3.	Therapeutics
4.	Radiotherapy
5.	Microspheres (Microsphere)