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5-hydroxyuridine
Also Known As:
isobarbituridine
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidine Nucleosides: 50
Uridine: 1186
5-hydroxyuridine: 2
Nucleic Acids, Nucleotides, and Nucleosides: 1
Nucleosides: 6847
Pyrimidine Nucleosides: 50
Uridine: 1186
5-hydroxyuridine: 2
Ribonucleosides: 49
Uridine: 1186
5-hydroxyuridine: 2
Related Diseases
1.
Vesicular Stomatitis
02/01/1978 - "
Alkylation of 5-hydroxyuridine or 5-hydroxy-2'-deoxyuridine with various activated alkylating agents in the presence of 1 equiv of NaOH gave a series of new nucleoside analogues which were evaluated for antiviral activity against vaccinia virus, herpes simplex-1 virus, and vesicular stomatitis virus in both primary rabbit kidney cells and human skin fibroblasts.
"
2.
Colonic Neoplasms (Colon Cancer)
07/01/1985 - "
Selective cytotoxicity of 5-hydroxyuridine for human colon adenocarcinoma cells.
"
07/01/1985 - "
The cytotoxicity of 5-hydroxyuridine (OHUrd), 5-FU, and 5-fluorodeoxyuridine was determined by colony assays for three human colon adenocarcinoma cell lines and for a cell line derived from normal fetal intestinal cells.
"
Related Drugs and Biologics
1.
Nucleosides
2.
Fluorouracil (Carac)
3.
Floxuridine (FUdR)
4.
Antiviral Agents (Antivirals)
5.
Alkylating Agents
6.
5-hydroxy-2'-deoxyuridine