L 9146

RN & NM given refers to HCl; structure

Also Known As:

2-methyl-3-(3,5-dimethyl-4-gamma-di-n-butylaminopropoxybenzoyl)benzo(b)thiophene hydrochloride; L-9146; methanone, (4-(3-(dibutylamino)propoxy)-3,5-dimethylphenyl)(2-methylbenzo(b)thien-3-yl)-, hydrochloride

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzofurans: 26
      - Amiodarone: 5571
        L 9146: 1

Related Diseases

1.	Tachycardia (Tachyarrhythmias) 01/01/1975 - "L 9146 has also antiadrenergic properties since catecholamine-induced hypertension, tachycardia and increase of myocardial oxygen consumption are markedly antagonized; these antiacrenergic effects are not due to a competitive blockade of the beta-adrenoceptors. "
2.	Hypertension (High Blood Pressure) 01/01/1975 - "L 9146 has also antiadrenergic properties since catecholamine-induced hypertension, tachycardia and increase of myocardial oxygen consumption are markedly antagonized; these antiacrenergic effects are not due to a competitive blockade of the beta-adrenoceptors. "
3.	Angina Pectoris 01/01/1975 - "The overall haemodynamic properties of L 9146, which are similar to those of amiodarone, are considered to be potentially valuable for the long-term treatment of angina pectoris."

Related Drugs and Biologics

1.	Adrenergic Receptors (Adrenergic Receptor)
2.	Catecholamines
3.	Amiodarone (Amiodarona)