monogalactosyldiacylglycerol

one galactose residue bound to diacylglycerol; plant MGDG are largely polyunsaturated fatty acids, especially 18:3 linoleic; constitutes half of plant chloroplast lipids; see also record for 1,2-distearoylmonogalactosylglyceride; the di-Gal DGDG is also available

Also Known As:

Networked: 7 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Ohta, Hiroyuki: 2 articles (01/2017 - 01/2009)
2.	Chen, Yi-Huan: 1 article (01/2022)
3.	Cui, Zhi-Quan: 1 article (01/2022)
4.	Du, Jing: 1 article (01/2022)
5.	Guo, Lin: 1 article (01/2022)
6.	Li, Rui: 1 article (01/2022)
7.	Peng, Zheng-Wu: 1 article (01/2022)
8.	Tan, Qing-Rong: 1 article (01/2022)
9.	Xue, Fen: 1 article (01/2022)
10.	Yang, Jia-Bin: 1 article (01/2022)

Related Diseases

1.	Human Influenza (Influenza) 09/03/2017 - "Therefore, a novel adjuvanted antigen delivery system, tubular immunostimulating complexes (TI-complexes) comprising monogalactosyldiacylglycerol (MGDG) from different marine macrophytes as a lipid matrix for an antigen, was applied to enhance the immunogenicity of recombinant HA1 of influenza A H1N1 and to study the relation between its immunogenicity and conformation. "
2.	Starvation 01/01/2017 - "Pulse-chase labeling experiments using plants grown under N-depleted conditions showed that, in pah1 pah2 plants, the labeling percent of chloroplast lipids such as phosphatidylglycerol and monogalactosyldiacylglycerol in the total glycerolipids was significantly lower than in WT. Moreover, N starvation-induced degradation of chloroplast structure was enhanced in pah1 pah2 mutants, and the membrane structure was recovered by complementation with PAH1. " 01/01/2009 - "Type-B monogalactosyldiacylglycerol synthases are involved in phosphate starvation-induced lipid remodeling, and are crucial for low-phosphate adaptation."
3.	Neoplasms (Cancer) 12/11/2014 - "The plant galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) have been linked to the anti-inflammatory and cancer benefits of a green leafy vegetable diet in humans due to their ability to regulate the levels of free radicals like nitric oxide (NO). "
4.	Leukemia 06/01/2000 - "Bacterial monogalactosyldiacylglycerol M874B (MGDAG), which protects against oxygen radicals, was found to increase the growth of the human promyelocytic leukemia cell HL60 when added to the cell culture, but suppresses the 12-O-tetradecanoyl phorbol-13-acetate-induced differentiation. "
5.	Breast Neoplasms (Breast Cancer) 05/15/2016 - "We purified monogalactosyldiacylglycerol (MGDG) from extracts of CL (CL-MGDG) and showed that it was the active CL component through analyses of its effects on the expression of genes of human breast cancer cell line, SKBR-3. "

Related Drugs and Biologics

1.	Lipids
2.	ISCOMs
3.	Antigens
4.	Phosphates (Orthophosphate)
5.	Galactolipids
6.	Reactive Oxygen Species (Oxygen Radicals)
7.	Triglycerides (Triacylglycerol)
8.	Sphingomyelins
9.	Phosphatidylserines
10.	Phosphatidylinositols (Phosphatidylinositol)