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bradykininogen

Networked: 16 relevant articles (2 outcomes, 4 trials/studies)

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Bio-Agent Context: Research Results

Related Diseases

1.	Liver Diseases (Liver Disease) 05/01/1972 - "Studies on the prekallikrein-bradykininogen system in liver disease." 05/01/1972 - "The plasma prekallikrein-bradykininogen system was studied in 45 patients with chronic liver disease since its activation with increased liberation of kinin into the plasma could account for some of the clinical manifestations of cirrhosis, namely, vasodilatation, hypotension, and increased capillary permeability.A significant reduction in plasma bradykininogen was found in the cirrhotic patients as compared with control groups of normal subjects and hospital inpatients. "
2.	Anaphylaxis (Anaphylactic Shock) 01/01/1984 - "It was demonstrated that anaphylactic shock was accompanied by the activation of the blood and lymph kinin system, manifesting in a decrease in the bradykininogen level and a rise in the content of free kinins in both body fluids. " 09/01/1969 - "1. Sodium phenylbutazone, soya bean trypsin inhibitor, or the concomitant administration of ascorbic acid and mepyramine protected rats against anaphylactic shock at 10 days after sensitization but gave no protection against anaphylaxis at 20 days.2. During anaphylactic shock in rats at 10 days after sensitization, the plasma bradykinin and bradykininogen levels, as well as those in the intestinal lumen and peritoneal cavity, were markedly raised.3. The results support the hypothesis that there are two phases in anaphylaxis in the rat-an early phase in which bradykinin is a mediator and against which phenylbutazone or soya bean trypsin inhibitor or the mixture of ascorbic acid and mepyramine, give protection, and a late phase which does not involve bradykinin."
3.	Hypotension (Low Blood Pressure) 05/01/1972 - "The plasma prekallikrein-bradykininogen system was studied in 45 patients with chronic liver disease since its activation with increased liberation of kinin into the plasma could account for some of the clinical manifestations of cirrhosis, namely, vasodilatation, hypotension, and increased capillary permeability.A significant reduction in plasma bradykininogen was found in the cirrhotic patients as compared with control groups of normal subjects and hospital inpatients. "
4.	Fibrosis (Cirrhosis) 05/01/1972 - "The plasma prekallikrein-bradykininogen system was studied in 45 patients with chronic liver disease since its activation with increased liberation of kinin into the plasma could account for some of the clinical manifestations of cirrhosis, namely, vasodilatation, hypotension, and increased capillary permeability.A significant reduction in plasma bradykininogen was found in the cirrhotic patients as compared with control groups of normal subjects and hospital inpatients. "
5.	Hypertension (High Blood Pressure) 09/01/1966 - "[Study of the concentration of bradykininogen in hypertension]." 01/01/1969 - "Changes in level of bradykininogen and pressor activity in blood of rats with experimental hypertension."

Related Drugs and Biologics

1.	Bradykinin
2.	Prekallikrein
3.	Kinins
4.	Trypsin Inhibitors
5.	Sodium
6.	Pyrilamine (Mepyramine)
7.	Phenylbutazone (Butazolidin)
8.	Dihydrotachysterol (AT 10)
9.	Ascorbic Acid (Vitamin C)
10.	Serotonin (5 Hydroxytryptamine)