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buthiazide (butizide)
3-isobutyl analog of hydrochlorothiazide; structure
Also Known As:
butizide
; hydrochlorbuthiazide; isobutylhydrochlorothiazide; thiabutazide; 6-chloro-3,4-dihydro-3-isobutyl-2H-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide
Networked:
14
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazides: 1584
Benzothiadiazines: 3
Chlorothiazide: 366
Hydrochlorothiazide: 2897
buthiazide: 14
Sulfones: 534
Sulfonamides: 2809
Benzothiadiazines: 3
Chlorothiazide: 366
Hydrochlorothiazide: 2897
buthiazide: 14
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Benzothiadiazines: 3
Chlorothiazide: 366
Hydrochlorothiazide: 2897
buthiazide: 14
Related Diseases
1.
Heart Failure
04/30/1985 - "
The efficacy and tolerability of two combinations, namely 50 mg spironolactone + 20 mg furosemide (SF) or 50 mg spironolactone + 5 mg butizide (SB), were compared in a randomised intraindividual trial in 22 patients with congestive heart failure.
"
2.
Phototoxic Dermatitis (Phototoxicity)
01/01/1997 - "
A number of sulphonamide derived oral antidiabetics (chlorpropamide, glibenclamide, glipizide, gliquidone, glymidine, tolazamide and tolbutamide) and diuretics (bemetizide, bendroflumethiazide, benzylhydrochlorothaizide, bumetanide, butizide, chlortalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide and xipamide) were investigated for phototoxicity in a cell culture model.
"
01/01/1997 - "
The oral antidiabetics chlorpropamide, glibenclamide, glipizide, gliquiudone, glymidine, tolazamide and tolbutamide, and the diuretics bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, chlortalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide, and xipamide were investigated for potential phototoxicity in vitro using a cell culture model, and in vivo in hairless mice.
"
02/01/1996 - "
A number of sulphonamide-derived oral antidiabetics (chlorpropamide, glibenclamide, glipizide, gliquidone, glymidine, tolazamide and tolbutamide) and diuretics (bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, chloratalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide and xipamide) were investigated for phototoxicity in a cell culture model.
"
03/01/1997 - "
The sulphonamide-derived oral antidiabetics chlorpropamide, glibenclamide, glipizide, gliquidone, glymidine, tolazamide and tolbutamide, and the diuretics bemetizide, bendroflumethiazide, benzylhydrochlorothiazide, bumetanide, butizide, chlortalidone, furosemide, hydrochlorothiazide, hydroflumethiazide, indapamide, piretanide, polythiazide, trichlormethiazide and xipamide were investigated for phototoxicity in a cell culture model.
"
3.
Hypertension (High Blood Pressure)
05/15/1981 - "
[The combined use of alpha-methyldopa and butizide in the treatment of arterial hypertension].
"
07/01/1992 - "
[Potassium canrenoate and the combination of potassium canrenoate-butizide in the therapy of light to moderate arterial hypertension].
"
10/15/1981 - "
[A new drug combination: metipranolol with butizide in the treatment of arterial hypertension].
"
08/28/1965 - "
[Combined use of alpha-methyldopa, Rauwolfia alkaloids and thiabutazide in the treatment of arterial hypertension].
"
4.
Essential Hypertension
07/01/1992 - "
Therefore, K-canrenoate in combination with butizide is an effective and well tolerated drug in the treatment of mild to moderate essential hypertension.
"
12/08/1981 - "
[Treatment of benign essential hypertension with an association of spironolactone and thiabutazide: an open multicenter study in general practice (author's transl)].
"
03/21/1975 - "
[Spironolactone and thiabutazide in the treatment of essential hypertension (author's transl)].
"
03/21/1975 - "
The anti-hypertensive effect of spironolactone and thiabutazide was tested on 47 unselected patients with primary hypertension.
"
10/20/1978 - "
In 61 out-patients with essential hypertension, grade I or II, propranolol was administered alone in increasing doses (3 x 40 mg/d or 3 x 80 mg/d) or, if there was insufficient response, with a double or triple combination consisting additionally of spironolactone (50 mg/d)-thiabutazide (5 mg/d) and dihydralazine (3 x 25 mg/d).
"
5.
Gout
01/05/1973 - "
[The effect of spironolactone and thiabutazide on serum-uric acid and lipid levels in patients with gout and in healthy persons].
"
Related Drugs and Biologics
1.
Furosemide (Lasix)
2.
Spironolactone (Aldactone)
3.
Xipamide
4.
Trichlormethiazide (Naqua)
5.
Polythiazide
6.
Indapamide
7.
Hydroflumethiazide (Diucardin)
8.
Hydrochlorothiazide (Esidrix)
9.
Bumetanide (Bumex)
10.
Bendroflumethiazide (Naturetin)
Related Therapies and Procedures
1.
Therapeutics