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wortmannin

inhibits PI3-kinase; inhibits alloantigen-specific T cell activation and cytotoxic T cell responses in human tumor cell lines
Also Known As:
MS 54; MS-54; (1 alpha,11 alpha)-11-(acetyloxy)-1-(methoxymethyl)-2-oxaandrosta-5,8-dieno(6,5,4-bc)furan- 3,7,17-trione
Networked: 500 relevant articles (21 outcomes, 36 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Yu, Huang-Ping: 6 articles (07/2012 - 06/2007)
2. Bland, Kirby I: 6 articles (12/2009 - 06/2007)
3. Chaudry, Irshad H: 6 articles (12/2009 - 06/2007)
4. Cohen, Michael V: 5 articles (10/2013 - 02/2003)
5. Downey, James M: 5 articles (10/2013 - 02/2003)
6. Hsu, Jun-Te: 5 articles (11/2012 - 10/2007)
7. Hsieh, Chi-Hsun: 5 articles (07/2011 - 10/2007)
8. Schwacha, Martin G: 5 articles (12/2009 - 06/2007)
9. Choudhry, Mashkoor A: 5 articles (08/2009 - 06/2007)
10. Yang, Xi-Ming: 4 articles (10/2013 - 01/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Ischemia
3. Sepsis (Septicemia)
4. Carcinoma (Carcinomatosis)
5. Neuroblastoma

Related Drugs and Biologics

1. Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)
2. 2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- one
3. Insulin (Novolin)
4. DNA (Deoxyribonucleic Acid)
5. Glucose (Dextrose)
6. Insulin-Like Growth Factor I (IGF-1)
7. Cisplatin (Platino)
8. Sirolimus (Rapamycin)
9. Small Interfering RNA (siRNA)
10. Carbon Monoxide

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)
2. Aftercare (After-Treatment)
3. Resuscitation
4. Ischemic Postconditioning
5. Drug Therapy (Chemotherapy)