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1,2,3-trichloropropane

Also Known As:
trichlorohydrin
Networked: 12 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Herbert, Ronald A: 2 articles (11/2020 - 07/2006)
2. Adams, David J: 1 article (11/2020)
3. Alexandrov, Ludmil B: 1 article (11/2020)
4. Balmain, Allan: 1 article (11/2020)
5. Campbell, Peter J: 1 article (11/2020)
6. Droop, Alastair: 1 article (11/2020)
7. Hewinson, James: 1 article (11/2020)
8. Iyer, Vivek: 1 article (11/2020)
9. Li, Yun Rose: 1 article (11/2020)
10. Pandiri, Arun R: 1 article (11/2020)

Related Diseases

1. Poisoning
2. Carcinogenesis
3. Neoplasms (Cancer)
08/01/1993 - "Neoplasms and Nonneoplastic Lesions in the 2-Year Studies: Administration of 1,2,3-trichloropropane to rats induced benign and malignant neoplasms of the oral mucosa (pharynx and tongue), forestomach, and preputial and clitoral glands in males and females; benign neoplasms of the exocrine pancreas and kidney in males, and malignant neoplasms of the mammary gland in females. "
09/01/1996 - "1,2,3-Trichloropropane (TCP) induces high incidences of tumors at multiple sites in mice and rats when administered chronically by gavage. "
05/01/1995 - "1,2,3-Trichloropropane induced benign and/or malignant neoplasms at multiple sites in both rats and mice; this included increased incidences of benign and malignant neoplasms of the squamous epithelium of the oral mucosa and forestomach of male and female rats, benign neoplasms of the kidney and pancreas and benign or malignant neoplasms of the preputial gland in male rats, malignant neoplasms of the mammary gland, and benign or malignant neoplasms of the clitoral gland in female rats. "
07/01/1990 - "Preliminary investigations into the role of biotransformation in 1,2,3-trichloropropane (TCP)-induced tumor formation have been undertaken. "
05/01/1995 - "In mice, 1,2,3-trichloropropane induced a low incidence of malignant neoplasms of the oral mucosa in females, high incidences of benign and malignant neoplasms of the forestomach in males and females, benign neoplasms of the liver and harderian gland of males and females, and uterine neoplasms in females."
4. Body Weight (Weight, Body)
5. Papilloma (Papillomatosis)

Related Drugs and Biologics

1. Corn Oil (Oil, Corn)
2. 2,2-bis(bromomethyl)-1,3-propanediol
3. nitromethane
4. Drinking Water
5. Trifluridine (Viroptic)
6. Solvents
7. Ethyl Chloride (Chloroethane)
8. Environmental Pollutants (Pollutants, Environmental)
9. Cobalt
10. Chloroform (Trichloromethane)

Related Therapies and Procedures

1. Plasma Exchange
2. Hemoperfusion