HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

surfactin peptide

antineoplastic product isolated from Bacillus sp.

Also Known As:

surfactin C

Networked: 4 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - surfactin peptide: 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Lipopeptides: 626
    - surfactin peptide: 4
  - Cyclic Peptides: 530
    - surfactin peptide: 4
Lipids: 114793
- Lipopeptides: 626
  - surfactin peptide: 4

Experts

1.	Hwang, Youn-Hwan: 2 articles (03/2009 - 02/2007)
2.	Lim, Jong Hwan: 2 articles (03/2009 - 06/2006)
3.	Yun, Hyo In: 2 articles (03/2009 - 06/2006)
4.	Kim, Myoung Seok: 1 article (03/2009)
5.	Park, Byung Kwon: 1 article (03/2009)
6.	Song, In Bae: 1 article (03/2009)
7.	Hwang, Mi-Hyun: 1 article (02/2007)
8.	Kim, Myoung-Seok: 1 article (02/2007)
9.	Lim, Jong-Hwan: 1 article (02/2007)
10.	Park, Byung-Kwon: 1 article (02/2007)

Related Diseases

1.	Septic Shock (Toxic Shock Syndrome) 02/05/2007 - "Surfactin C not only completely bound to the LPS (its median effective concentration being 13.75 microM) but also improved the survival and reduced of the number of inoculated bacteria in the mouse model of septic shock. " 02/05/2007 - "Lipopolysaccharide-binding and neutralizing activities of surfactin C in experimental models of septic shock." 02/05/2007 - "To evaluate the anti-endotoxin activity of surfactin C, we studied its lipopolysaccharide-binding activity in vitro and therapeutic efficacy in experimental models of gram-negative septic shock. " 02/05/2007 - "Surfactin C reduced the plasma endotoxin, tumor necrosis factor-alpha and nitric oxide levels in response to septic shock in rats."
2.	Pulmonary Embolism 04/29/2002 - "In a rat pulmonary embolism model, surfactin C (1 mg/kg, i.v.) elevated 125I plasma clot lysis when injected in combination with pro-u-PA. "
3.	Chromosome Aberrations (Chromosome Abnormalities) 03/01/2009 - "These results showed that surfactin C was not capable of inducing chromosome aberration, as measured by the chromosome aberration test using Chinese hamster lung cell line. " 03/01/2009 - "The IC50 value was 125 μg/ml. For the chromosome aberration test of surfactin C, the maximum concentration was employed as 125 μg/ml, followed by 62.5 and 31.25 μg/ml for the lower concentrations, with or without metabolic activation (S9). " 03/01/2009 - "To investigate the mutation inducibility of surfactin C, we performed the chromosome aberration assay with Chinese hamster lung cells in vitro. "
4.	Cardiovascular Diseases (Cardiovascular Disease) 06/01/2006 - "Therefore, the results suggest that surfactin C may have a beneficial therapeutic effect on aberrant platelet aggregation-mediated cardiovascular diseases."

Related Drugs and Biologics

1.	Lipopolysaccharides
2.	Endotoxins
3.	Therapeutic Uses
4.	Urokinase-Type Plasminogen Activator (Urokinase)
5.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
6.	Nitric Oxide (Nitrogen Monoxide)