sorbitan monostearate (Span 60)

01/01/2018 - "Despite a higher accumulation of Tween-60 niosomes in tumor, the Span 60 formulation showed the highest antitumor efficacy when compared with the free drug (71.7 and 20.3% inhibition in tumor growth, respectively). "
09/01/1960 - "Histopathology of tumors induced in mice treated with polyoxyethylene sorbitan monostearate."
01/01/2021 - "This study evaluated the cellular uptake and cytotoxicity of low permeable Ursolic acid (UA) on cancer cells using niosomes composed of span 60 and cholesterol. "
01/01/1961 - "The effect of five ulcerating doses of alkyldimethylbenzylammoniumchloride (Zephiran) on the tumor promoting action of polyoxyethylene sorbitan monostearate (tween 60). "
01/01/1980 - "As part of an attempt to uncover the molecular basis of tumor promotion, the effects of the tumor promoters 12-0-tetradecanoylphorbol-13-acetate (TPA), sodium dodecyl sulfate, cholic acid and polyoxyethylene sorbitan monostearate (Tween 60) on conformations of histones in 0.14 M NaF, pH 7.8, were studied by the circular dichroism technique. "

01/01/1996 - "Demonstration of the improved doxorubicin pharmacokinetics and tumoricidal activity, after a single intravenous dose of 10mg kg-1 doxorubicin sorbitan monostearate (Span 60) based niosomes in the mouse adenocarcinoma (MAC) tumour model (Uchegbu et al., 1995) preceded the present study in which the activity of doxorubicin C16G2 (a hexadecyl diglycerol ether) based niosomes was evaluated against naive and established MAC tumour models. "

04/30/2017 - "The aim of this research was to encapsulate ciprofloxacin, a broad spectrum fluoroquinolone antibiotic, into Span 60 based nano-elastic vesicles, nano-spanlastics, for accomplishing improved non invasive trans-tympanic delivery, providing means for ototopical treatment of acute otitis media (AOM). "

09/01/1960 - "Role of polyoxyethylene sorbitan monostearate in skin carcinogenesis in mice."
01/01/1959 - "Studies of the action of polyoxyethylene sorbitan monostearate (tween 60) in skin carcinogenesis in the mouse."

04/01/2002 - "In the present study niosomes of cisplatin by using span 60 and cholesterol were prepared and investigated for antimetastatic activity in experimental metastatic model of B16F10 melanoma. "