|1.||Li, Jian-Xin: 5 articles (06/2015 - 03/2008)|
|2.||Liu, Liang: 3 articles (08/2015 - 10/2008)|
|3.||Zhang, Jingbo: 3 articles (04/2013 - 08/2005)|
|4.||Teng, Peng: 3 articles (04/2013 - 03/2008)|
|5.||Li, Peng: 3 articles (02/2013 - 03/2008)|
|6.||Deng, Zhang-Shuang: 3 articles (04/2012 - 03/2008)|
|7.||Zhao, Yang: 2 articles (08/2015 - 06/2015)|
|8.||He, Jianjun: 2 articles (08/2015 - 01/2015)|
|9.||Zhou, Hua: 2 articles (08/2015 - 11/2008)|
|10.||Wang, Ting: 2 articles (05/2015 - 03/2014)|
10/01/1996 - "In-acute AIA, short and middle-term treatment with sinomenine around and following induction of arthritis induced a dose-dependent decrease of both joint swelling and ESR, starting after the peak of arthritis, and a significant reduction of joint destruction on day 3. There was no rebound of the arthritic signs following suspension of treatment. "
06/01/2015 - "The aim of the present study was to examine the anti-arthritis effects of SND-117, a sinomenine bivalent that is obtained from the structure modification of a clinically available anti-RA drug, sinomenine. "
05/01/2007 - "Sinomenine, a purified alkaloid extracted from Sinomenium acutum, has been employed to treat arthritis for a long time. "
03/15/2007 - "Sinomenine, an herbal ingredient isolated from Sinomenium acutum, is used for the amelioration of arthritis. "
04/11/2003 - "Sinomenine, an herbal ingredient isolated from Sinomenium acutum, is used for the amelioration of arthritis. "
|2.||Breast Neoplasms (Breast Cancer)
01/01/2012 - "This double-blinded, placebo-controlled, randomised Phase III study showed that adding a complex homeopathic medicine (Cocculine) to standard anti-emetic prophylaxis does not improve the control of CINV in early breast cancer patients."
08/28/2015 - "Here, we report that sinomenine suppressed the invasion and migration of MDA-MB-231 and 4T1 breast cancer cells in a dose-dependent manner. "
08/28/2015 - "Sinomenine inhibits breast cancer cell invasion and migration by suppressing NF-κB activation mediated by IL-4/miR-324-5p/CUEDC2 axis."
01/01/2012 - "A randomized, placebo-controlled Phase III study was conducted to evaluate the efficacy of a complex homeopathic medicine, Cocculine, in the control of CINV in non-metastatic breast cancer patients treated by standard chemotherapy regimens. "
08/28/2015 - "However, the role and mechanism of sinomenine in invasion and metastasis of breast cancer are largely unknown. "
|3.||Neuralgia (Stump Neuralgia)
01/01/2014 - "Together, these results suggested that sinomenine exerts significant antinociceptive effects for neuropathic pain via GABAa-mediated mechanism, which suggests that sinomenine may be useful for the management of chronic painful conditions such as neuropathic pain."
01/01/2014 - "This study examined the effects of sinomenine in rats that received chronic constriction injury (CCI), a model of peripheral neuropathic pain. "
12/05/2013 - "In the present study, we evaluated the potential antinociceptive effects of sinomenine in rodents with nociceptive, inflammatory and neuropathic pain. "
01/01/2014 - "Antinociceptive effects of sinomenine in a rat model of neuropathic pain."
12/05/2013 - "Our results showed that sinomenine has a wide spectrum analgesic effect in rodent models of nociceptive, inflammatory and neuropathic pain. "
01/01/2013 - "Our study evaluated the effects and potential mechanisms of sinomenine in the anti-inflammatory response via miRNA-155 in mice with TNBS-induced colitis. "
05/01/2007 - "The aim of the present study was to evaluate therapeutic effects of sinomenine on 2, 4, 6-trinitrobenzene sulfonic acid (TNBS) induced colitis in mice. "
01/01/2013 - "Furthermore, sinomenine at a dose of 200 mg/kg significantly decreased the level of miR-155 expression by 71% (p = 0.025) compared with untreated TNBS-induced colitis in mice. "
01/01/2013 - "After colitis was induced in mice by instillation of 5% (w/v) 2,4,6-trinitrobenzenesulfonic acid (TNBS), sinomenine at a dose of 100 or 200 mg/kg was orally administered once daily for 7 days. "
01/01/2013 - "Effects of sinomenine on the expression of microRNA-155 in 2,4,6-trinitrobenzenesulfonic acid-induced colitis in mice."
10/01/2013 - "Sinomenine (SIN) is the active principle of the Chinese medical plant Sinomenium acutum which is widely used for the treatment of rheumatoid arthritis (RA) in China. "
09/04/2008 - "In a continuing study on discovery of more potent derivatives of sinomenine (1), a clinically available alkaloid for rheumatoid arthritis (RA) treatment, oxidation of sinomenine provided two unique stereoisomers, disinomenines 2 and 3. The structure of 3 was determined by MS, NMR, and X-ray analysis. "
08/01/2015 - "Sinomenine (SIN), an alkaloid derived from the plant Sinomenium acutum, has anti-inflammatory and analgesic effects and has been used for rheumatoid arthritis treatment in China. "
06/01/2015 - "Sinomenine is an anti-rheumatoid arthritis (RA) drug derived from the Sinomenium acutum. "
05/01/2015 - "Sinomenine (SIN) has long been used as a therapeutic agent of rheumatoid arthritis (RA) in China. "
|6.||Histamine (Histamine Dihydrochloride)
|8.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
|9.||Interleukin-1beta (Interleukin 1 beta)
|10.||Interferon-gamma (Interferon, gamma)
|1.||Drug Therapy (Chemotherapy)
|4.||Homologous Transplantation (Allograft)
|5.||Transplantation (Transplant Recipients)